Women's CBB- More Betting
Cal Poly vs. USC prediction: USC favored to win women's college basketball matchup [12/18/2025]
Get Cal Poly vs USC predictions for college basketball Thursday.

USC will take on Cal Poly in women's college basketball action at Galen Center on Thursday, commencing at 10:00 PM ET.
Based on updated simulation results, Dimers' new women's basketball model predicts USC as the most likely winner of the Cal Poly vs. USC game.
This article offers further insights into Thursday's matchup, including best bets and picks.
Cal Poly vs. USC prediction: Who will win?
Using powerful machine learning and data, we have simulated the result of Thursday's women's basketball game between Cal Poly and USC 10,000 times as part of our women's college basketball predictions coverage.
Our famous predictive model currently gives USC a 99% chance of beating Cal Poly.
According to our model, the 129.5-point over/under has a 51% chance of going over.
Cal Poly vs. USC odds
We have researched the best women's college basketball odds in America for this game, which are listed here:
| Bet Type | Cal Poly | USC |
|---|---|---|
| Spread | +56.5 (-110) | -56.5 (-110) |
| Total | o129.5 (-110) | u129.5 (-110) |
All odds are correct at the time of publication and are subject to change.
Cal Poly vs. USC picks and best bet
After matching our probabilities against the best current odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:
| Bet Type | Pick | Bet Now |
|---|---|---|
| Spread | Cal Poly +56.5 | -110 |
| Total | Over 129.5 | -110 |
According to our women's college basketball best bets, the top play to make on this game is Cal Poly +56.5.
Cal Poly vs. USC game-day updates and essential details
Thursday's women's basketball matchup between USC and Cal Poly at Galen Center is scheduled to start at 10:00 PM ET.
- Who: Cal Poly vs. USC
- Date: Thursday, December 18, 2025
- Time: 10:00 PM ET/7:00PM PT
- Venue: Galen Center
Conclusion
We predict USC, with a 99% win probability, will likely beat Cal Poly on Thursday.
AI and automation have enhanced this article to quickly deliver accurate Cal Poly vs. USC insights, with human oversight ensuring high editorial quality. Our predictions are sourced from up-to-date data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.
Note: Clicking links to our partners may earn us a referral fee. Learn about how we review products and services.
