Butler vs. Xavier prediction: Butler favored to win men's college basketball matchup [1/14/2026]

Xavier will take on Butler, in what is expected to be a tight Men's College Basketball game, at Cintas Center on Wednesday, beginning at 6:30 PM ET.

Based on the latest simulation results, Dimers' proven college basketball model gives Butler a slight edge with a 54% win probability over Xavier.

This article offers further insights into Wednesday's Butler vs. Xavier matchup, including an expanded look at the predicted score, best bets and picks.

Butler vs. Xavier prediction: Who will win and cover?

Using trusted machine learning and data, we have simulated the outcome of Wednesday's NCAA basketball game between Butler and Xavier 10,000 times as part of our men's college basketball predictions coverage.

Our famous predictive model gives Butler a 54% chance of beating Xavier. Our predicted final score has Butler winning 78-77.

According to our model, Xavier (+1.5) has a 51% chance of covering the spread, while the over/under total of 159.5 points has a 53% chance of staying under.

Butler vs. Xavier odds

We have sourced the best men's college basketball odds in America for this game, which are listed here:

All odds are correct at the time of publication and are subject to change.

Butler vs. Xavier picks and best bet

After matching our predictions against the best current odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below: