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Buffalo vs. Canisius prediction: Why Buffalo is favored to win men's college basketball matchup [11/29/2025]
Get Buffalo vs Canisius predictions for college basketball Saturday.

Men's college basketball action continues on Saturday at 6:00PM ET as the favored Buffalo takes on Canisius in men's college basketball action at Koessler Athletic Center.
Based on updated simulation results, Dimers' proven college basketball model predicts Buffalo as the most likely winner of the Buffalo vs. Canisius game.
This article offers an expanded analysis of Saturday's matchup, including an expanded look at the predicted score, best bets and picks.
Buffalo vs. Canisius prediction: Who will win and cover?
Using innovative machine learning and data, we have simulated the outcome of Saturday's NCAA basketball game between Buffalo and Canisius 10,000 times as part of our men's college basketball predictions coverage.
Our leading predictive model currently gives Buffalo an 83% chance of beating Canisius. Our predicted final score has Buffalo winning 75-65.
According to our model, Buffalo (-8.5) has a 55% chance of covering the spread, while the 139.5-point over/under has a 51% chance of staying under.
Buffalo vs. Canisius odds
We have researched the best men's college basketball odds in America for this game, which are listed here:
| Bet Type | Buffalo | Canisius |
|---|---|---|
| Spread | -8.5 (-115) | +8.5 (-102) |
| Moneyline | -450 | +350 |
| Total | o139.5 (-110) | u139.5 (-105) |
All odds are correct at the time of publication and are subject to change.
Buffalo vs. Canisius picks and best bet
After matching our probabilities against the best current odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:
| Bet Type | Pick | Bet Now |
|---|---|---|
| Spread | Buffalo -8.5 | -115 |
| Moneyline | Buffalo | -450 |
| Total | Under 139.5 | -105 |
According to our men's college basketball best bets, the top play to make on this game is Buffalo -8.5 at the spread.
Buffalo vs. Canisius game-day updates and essential details
Saturday's men's college basketball matchup between Canisius and Buffalo at Koessler Athletic Center is scheduled to commence at 6:00PM ET.
- Who: Buffalo vs. Canisius
- Date: Saturday, November 29, 2025
- Time: 6:00PM ET/3:00PM PT
- Venue: Koessler Athletic Center
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Conclusion
We predict Buffalo, with an 83% win probability, will likely beat Canisius on Saturday.
AI and automation have enhanced this article to quickly deliver accurate Buffalo vs. Canisius insights, with human oversight ensuring high editorial quality. Our predictions are drawn from the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.
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