Buffalo Bills vs. Denver Broncos updated prediction featuring James Cook, RJ Harvey [Divisional Round, 2026]

Dimers' latest NFL predictions are live for Denver Broncos vs. Buffalo Bills in Divisional Round of the playoffs, with our model giving the Broncos a 56% of winning.

As Saturday approaches, both teams have updated their injury reports. Some lineup calls are still undecided, and those could shape how each side approaches this AFC clash.

Since our early Broncos-Bills predictions, we’ve updated the win probabilities, score projections, and TD odds for James Cook, RJ Harvey, and others.

For the full simulation breakdown—including spreads, totals, touchdown probabilities, and the full list of player props—check out our Bills vs. Broncos page.

What's changed? Buffalo vs. Denver updated predictions

Our NFL predictions model has been re-run with the newest available data, creating a clearer picture of how this Bills vs. Broncos matchup stacks up. Here are the updated forecasts:

• Straight Up Win Probabilities: Bills 44%, Broncos 56%
• Predicted Final Score: Bills 21-23 Broncos
• Spread: Bills (+1.5) 50%, Broncos (-1.5) 50%
• Total Points (46.5): Over 48%, Under 52%

As of January 15, 2026, these Bills-Broncos figures reflect changes since our early-week simulation.

Anytime touchdown scorer predictions

New NFL player projections for the Divisional Round highlight the top candidates to find the end zone in Bills-Broncos on Saturday:

Buffalo Bills

• James Cook: 50.5% probability
• Josh Allen: 47.7% probability
• Khalil Shakir: 27.1% probability

Denver Broncos

• RJ Harvey: 51.4% probability
• Courtland Sutton: 30.9% probability
• Bo Nix: 21.5% probability

Bills vs. Broncos latest odds

The best current odds from the top sportsbooks in the US:

• Spread: Bills +1.5 (-115), Broncos -1.5 (-102)
• Moneyline: Bills -102, Broncos -115
• Total: Over/Under 46.5 (-105/-115)

Odds are correct at time of publication and are subject to change—track live updates via our NFL odds page.

Bills vs. Broncos Divisional Round details

Saturday's game between the Broncos and Bills at Empower Field at Mile High is scheduled for January 17, 2026.

• Who: Buffalo Bills vs. Denver Broncos
• Date: Saturday, January 17, 2026
• Time: 4:30 PM ET/1:30PM PT
• Venue: Empower Field at Mile High

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Conclusion

We predict the Broncos, with a 56% win probability, will likely beat the Bills in this NFL postseason matchup. Dimers.com will provide full game coverage closer to kickoff, so stay tuned for updates.

Enhanced by AI and automation, this article delivers quick, accurate insights on the Bills vs. Broncos matchup, with human oversight maintaining high editorial quality. Our predictions are based on up-to-date data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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