Nets vs. Pacers prediction: Why Indiana is favored to win Wednesday's NBA matchup [11/5/2025]

The Indiana Pacers will take on the Brooklyn Nets in NBA action at Gainbridge Fieldhouse on Wednesday, commencing at 7:00PM ET.

Based on the latest simulation results and today’s injury news, Dimers' advanced NBA model predicts the Pacers as the most likely winner of the Nets vs. Pacers game.

This prediction follows the latest NBA Injury Report, which suggests the Pacers lineup will feature stars like Pascal Siakam, Aaron Nesmith and Jarace Walker, while the Nets will be led by Cam Thomas, Michael Porter and Nic Claxton.

This article offers an expanded analysis of Wednesday's matchup, including an expanded look at the predicted score, best bets and player prop picks.

Nets vs. Pacers prediction: Who will win, cover the spread?

Using trusted machine learning and data analysis, we have simulated the result of Wednesday's NBA matchup between the Nets and Pacers 10,000 times as part of our NBA predictions coverage.

Our independent predictive model gives the Pacers a 70% chance of beating the Nets. Our predicted final score has the Pacers winning 119-113.

According to our model, the Nets (+6.5) have a 52% chance of covering the spread, while the over/under total of 232.5 points has an equal 50-50 chance of hitting.

Nets vs. Pacers odds

We have sourced the best NBA odds in America for this game, which are listed here:

All odds are correct at the time of publication and are subject to change.

Nets vs. Pacers picks and best bet

After matching our predictions against the best current odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:

According to our best NBA bets for Wednesday, the top play to make on this game is Nets +6.5 at the spread.

Nets vs. Pacers player props

NBA prop bets are a common way to wager on the Nets vs. Pacers matchup without necessarily betting on the outcome. We use the best information available to project how each team's leading players will perform at Gainbridge Fieldhouse.

Cam Thomas is expected to lead the Nets with 23 points, 3 rebounds and 3 assists, while Pascal Siakam is projected to have 25 points, 7 rebounds and 5 assists for the Pacers.

Check out our NBA player projections for a full range of projected box scores, including points, assists, rebounds and more, for every game this season.

Nets prediction

Our model's projected player stats for the Nets are:

Pacers prediction

Projected points, rebounds, assists and three-pointers made for the Pacers:

Nets vs. Pacers game-day updates and essential details

Wednesday's action between the Pacers and Nets at Gainbridge Fieldhouse is scheduled to begin at 7:00PM ET.

• Who: Brooklyn Nets vs. Indiana Pacers
• Date: Wednesday, November 5, 2025
• Time: 7:00PM ET/4:00PM PT
• Venue: Gainbridge Fieldhouse

Conclusion

We predict the Pacers, with a 70% win probability, will likely beat the Nets on Wednesday.

AI and automation have enhanced this article to quickly deliver accurate Nets vs. Pacers insights, with human oversight ensuring high editorial quality. Our predictions are drawn from the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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