Boston University vs. Lafayette prediction: Boston University favored to win men's college basketball matchup [1/7/2026]

Lafayette will face Boston University in men's college basketball action at Kirby Sports Center on Wednesday, beginning at 7:00 PM ET.

Based on the latest simulation results, Dimers' advanced college basketball model predicts Boston University as the most likely winner of the Boston University vs. Lafayette game.

This article offers further insights into Wednesday's matchup, including an expanded look at the predicted score, best bets and picks.

Boston University vs. Lafayette prediction: Who will win and cover?

Using innovative machine learning and data, we have simulated the result of Wednesday's NCAA basketball matchup between Boston University and Lafayette 10,000 times as part of our men's college basketball predictions coverage.

Our leading predictive model gives Boston University a 59% chance of beating Lafayette. Our predicted final score has Boston University winning 72-70.

According to our model, Boston University (-1.5) has a 53% chance of covering the spread, while the over/under total of 142.5 points has an equal 50-50 chance of hitting.

Boston University vs. Lafayette odds

We have researched the best men's college basketball odds in America for this game, which are listed here:

All odds are correct at the time of publication and are subject to change.

Boston University vs. Lafayette picks and best bet

After matching our predictions against the best current odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below: