Red Sox vs. Blue Jays prediction: Why Toronto is favored to win Monday's MLB matchup [4/27/2026]

The Toronto Blue Jays will face the Boston Red Sox in MLB action at Rogers Centre on Monday, commencing at 7:07 PM ET.

The Blue Jays will have Dylan Cease (1-0, 2.10 ERA) as their starting pitcher, while the Red Sox have opted for Ranger Suarez (1-2, 4.00 ERA).

Based on updated simulations, Dimers' proven MLB model predicts the Blue Jays as the most likely winner of the Red Sox vs. Blue Jays game.

This article offers an expanded analysis of Monday's matchup, including best bets and picks.

Red Sox vs. Blue Jays prediction: Who will win and cover?

Using powerful machine learning and data, we have simulated the outcome of Monday's MLB matchup between the Red Sox and Blue Jays, forming part of our MLB predictions coverage.

Our independent predictive model currently gives the Blue Jays a 57% chance of defeating the Red Sox.

According to our model, the Red Sox (+1.5) have a 61% chance of covering the run line, while the 7-run over/under has a 57% chance of going over.

Red Sox vs. Blue Jays odds [4/27/2026]

We have sourced the best MLB odds in America for this game, which are listed here:

All odds are correct at the time of publication and are subject to change.

Red Sox vs. Blue Jays picks and best bet

After matching our predictions against the best available odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below: