Boston College vs. Louisville prediction: Louisville favored to win men's college basketball matchup [1/10/2026]

Louisville will take on Boston College in men's college basketball action at KFC Yum! Center on Saturday, beginning at 12:00 PM ET.

Based on the latest simulations, Dimers' advanced college basketball model predicts Louisville as the most likely winner of the Boston College vs. Louisville game.

This article offers further insights into Saturday's matchup, including an expanded look at the predicted score, best bets and picks.

Boston College vs. Louisville prediction: Who will win and cover?

Using trusted machine learning and statistical analysis, we have simulated the outcome of Saturday's NCAA basketball matchup between Boston College and Louisville 10,000 times as part of our men's college basketball predictions coverage.

Our famous predictive model currently gives Louisville a 96% chance of beating Boston College. Our predicted final score has Louisville winning 86-65.

According to our model, Louisville (-20.5) has a 52% chance of covering the spread, while the 151.5-point over/under has a 57% chance of going over.

Boston College vs. Louisville odds

We have researched the best men's college basketball odds in America for this game, which are listed here:

All odds are correct at the time of publication and are subject to change.

Boston College vs. Louisville picks and best bet

After matching our probabilities against the best current odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below: