Celtics vs. Pistons prediction: Detroit favored to win Sunday's NBA matchup [10/26/2025]

The Detroit Pistons will square off with the Boston Celtics in NBA action at Little Caesars Arena on Sunday, starting at 3:30PM ET.

Based on updated simulations and today’s injury updates, Dimers' advanced NBA model projects the Pistons as the most likely winner of the Celtics vs. Pistons game.

This prediction follows the latest NBA Injury Report, which suggests the Pistons lineup will feature players like Cade Cunningham, Tobias Harris and Ausar Thompson, while the Celtics will look to Jaylen Brown, Derrick White and Anfernee Simons.

This article offers a closer look at Sunday's matchup, including an expanded look at the predicted score, best bets and player prop picks.

Celtics vs. Pistons prediction: Who will win, cover the spread?

Using trusted machine learning and data analysis, we have simulated the result of Sunday's NBA matchup between the Celtics and Pistons 10,000 times as part of our NBA predictions coverage.

Our leading predictive model currently gives the Pistons a 57% chance of beating the Celtics. Our predicted final score has the Pistons winning 114-112.

According to our model, the bookies have got it right, and the Celtics and Pistons each have a 50% chance of covering the spread, while the 227.5-point over/under also has an equal 50-50 chance of hitting.

Celtics vs. Pistons odds

We have sourced the best NBA odds in America for this game, which are listed here:

All odds are correct at the time of publication and are subject to change.

Celtics vs. Pistons picks and best bet

After matching our predictions against the best available odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:

According to our NBA best bets, the top play to make on this game is Pistons moneyline.

Celtics vs. Pistons player props

NBA player props are a common way to wager on the Boston vs. Detroit game without necessarily betting on the outcome. We have crunched the numbers to project how each team's leading players will perform at Little Caesars Arena.

Jaylen Brown is expected to lead the Celtics with 22 points, 6 rebounds and 4 assists, while Cade Cunningham is projected to have 26 points, 6 rebounds and 8 assists for the Pistons.

Check out our NBA player projections for a full range of projected box scores, including points, assists, rebounds and more, for every game this season.

Celtics prediction

Our model's projected player stats for the Celtics are:

Pistons prediction

Projected points, rebounds, assists and three-pointers made for the Pistons:

Celtics vs. Pistons game-day updates and essential details

Sunday's action between the Pistons and Celtics at Little Caesars Arena is scheduled to begin at 3:30PM ET.

• Who: Boston Celtics vs. Detroit Pistons
• Date: Sunday, October 26, 2025
• Time: 3:30PM ET/12:30PM PT
• Venue: Little Caesars Arena

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Conclusion

We predict the Pistons, with a 57% win probability, will likely beat the Celtics on Sunday.

AI and automation have enhanced this article to quickly deliver accurate Celtics vs. Pistons insights, with human oversight ensuring high editorial quality. Our predictions are based on the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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