Bethune-Cookman vs. Saint Louis prediction: Saint Louis favored to win men's college basketball matchup [12/17/2025]

Men's college basketball action continues on Wednesday at 8:00 PM ET as Bethune-Cookman takes on the favored Saint Louis in men's college basketball action at Chaifetz Arena.

Based on updated simulation results, Dimers' proven college basketball model predicts Saint Louis as the most likely winner of the Bethune-Cookman vs. Saint Louis game.

This article offers a closer look at Wednesday's matchup, including an expanded look at the predicted score, best bets and picks.

Bethune-Cookman vs. Saint Louis prediction: Who will win and cover?

Using powerful machine learning and data, we have simulated the result of Wednesday's NCAA basketball game between Bethune-Cookman and Saint Louis 10,000 times as part of our men's college basketball predictions coverage.

Our independent predictive model currently gives Saint Louis a 98% chance of defeating Bethune-Cookman. Our predicted final score has Saint Louis winning 91-65.

According to our model, Saint Louis (-26.5) has a 51% chance of covering the spread, while the 157.5-point over/under has an equal 50-50 chance of hitting.

Bethune-Cookman vs. Saint Louis odds

We have researched the best men's college basketball odds in America for this game, which are listed here:

All odds are correct at the time of publication and are subject to change.

Bethune-Cookman vs. Saint Louis picks and best bet

After matching our predictions against the best current odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below: