Atlanta Falcons vs. Arizona Cardinals updated prediction featuring Bijan Robinson, Trey McBride [Week 16, 2025]

Dimers' latest NFL predictions are live for Arizona Cardinals vs. Atlanta Falcons in Week 16, with our model giving the Falcons a 56% of winning.

As Sunday approaches, both teams have updated their injury reports. A few lineup decisions are still up in the air, and those could shape how each side approaches this NFC clash.

Since our early Cardinals-Falcons predictions, we’ve updated the win probabilities, score projections, and TD odds for Bijan Robinson, Trey McBride, and others.

For the full simulation breakdown—including spreads, totals, touchdown probabilities, and the full list of player props—check out our Falcons vs. Cardinals page.

What's changed? Atlanta vs. Arizona updated predictions

Our NFL predictions model has been re-run with the newest available data, creating a clearer picture of how this Falcons vs. Cardinals matchup stacks up. Here are the updated forecasts:

• Straight Up Win Probabilities: Falcons 56%, Cardinals 44%
• Predicted Final Score: Falcons 24-22 Cardinals
• Spread: Falcons (-2.5) 42%, Cardinals (+2.5) 58%
• Total Points (48.5): Over 47%, Under 53%

As of December 18, 2025, these Falcons-Cardinals numbers reflect changes since our early-week simulation.

Anytime touchdown scorer predictions

New NFL player projections for Week 16 highlight the top candidates to find the end zone in Falcons-Cardinals on Sunday:

Atlanta Falcons

• Bijan Robinson: 57.1% probability
• Drake London: 39.4% probability
• Tyler Allgeier: 37.1% probability

Arizona Cardinals

• Trey McBride: 44.6% probability
• Michael Wilson: 38.3% probability
• Marvin Harrison: 35.5% probability

Falcons vs. Cardinals latest odds

The best current odds from the top sportsbooks in the US:

• Spread: Falcons -2.5 (-115), Cardinals +2.5 (-105)
• Moneyline: Falcons -148, Cardinals +135
• Total: Over/Under 48.5 (-105/-115)

Odds are correct at time of publication and are subject to change—track live updates via our NFL odds page.

Falcons vs. Cardinals Week 16 details

The NFL Week 16 game between the Cardinals and Falcons at State Farm Stadium is scheduled for December 21, 2025.

• Who: Atlanta Falcons vs. Arizona Cardinals
• Date: Sunday, December 21, 2025
• Time: 4:05 PM ET/1:05PM PT
• Venue: State Farm Stadium

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Conclusion

We predict the Falcons, with a 56% win probability, will likely beat the Cardinals in Week 16 of the NFL season. Dimers.com will provide full game coverage closer to kickoff, so stay tuned for updates.

Enhanced by AI and automation, this article delivers quick, accurate insights on the Falcons vs. Cardinals matchup, with human oversight maintaining high editorial quality. Our predictions are based on the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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