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Diamondbacks vs. Padres Prediction: Arizona Predicted to Win Thursday's MLB Matchup [7/10/2025]

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Written by Dave Garofolo

Our expert prediction for Thursday's Arizona Diamondbacks vs San Diego Padres matchup.

Arizona Diamondbacks-San Diego Padres Predictions and Game Preview.
PETCO Park sets the stage for the MLB matchup between the Arizona Diamondbacks and San Diego Padres this Thursday.

The San Diego Padres and Arizona dbacks are scheduled to meet in MLB action at PETCO Park on Thursday, starting at 9:40PM ET.

The Padres will start Randy Vásquez (3-4, 3.79 ERA), while the Diamondbacks have opted for Eduardo Rodriguez (3-5, 5.78 ERA).

Based on updated simulation results, Dimers' proven MLB model (see Dimers Pro for full access) predicts the Diamondbacks as the most likely winner of today's game.

For further insights into Thursday's matchup, including best bets and picks, visit our interactive Diamondbacks vs. Padres predictions page.

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Padres vs. Diamondbacks Prediction: Who Will Win, Cover the Run Line?

Using trusted machine learning and data, we have simulated the result of Thursday's MLB matchup between the Diamondbacks and Padres 10,000 times as part of our MLB predictions coverage.

Our independent predictive model gives the Diamondbacks a 52% chance of beating the Padres.

According to our model, the Padres (+1.5) have a 61% chance of covering the run line, while the over/under total of 8.5 runs has an equal 50-50 chance of hitting.

Pre-Game Probabilities
Last Updated: 1:28AM, Jul 11
Moneyline
Over / Under
Run Line
D-Backs
Win %
53%
47%
Get the best bets with Dimers Pro
See Matchup
Padres
D-Backs ARI
Win %
53%
47%
See Matchup
Padres SD
Eduardo Rodriguez 3-5, 5.78 ERA
Randy Vásquez 3-4, 3.79 ERA
Get the best bets with Dimers Pro

Diamondbacks vs. Padres Odds [7/10/2025]

We have researched the best MLB odds in America for this game, which are listed here:

Bet Type Diamondbacks Padres
Run Line -1.5 (+140) +1.5 (-156)
Moneyline -124 +106
Total o8.5 (-119) u8.5 (+100)

All odds are correct at the time of publication and are subject to change.

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Diamondbacks vs. Padres Picks and Best Bets

Our model's strongest edge in today's Diamondbacks vs. Padres matchup is on the total.

Our expert predictions, aligned with the best odds, reveal the best MLB picks and MLB best bets for every game throughout the season.

Unlimited access to our complete suite of picks, including this one, is available via Dimers Pro.

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Calling Our Shot's Free MLB Picks

Calling Our Shot produces daily MLB betting content, including the free picks featured below.

Diamondbacks vs. Padres Game-Day Updates and Essential Details

Thursday's MLB matchup between the Padres and Diamondbacks at PETCO Park is scheduled to commence at 9:40PM ET.

Dimers.com's comprehensive preview of Thursday's Diamondbacks vs. Padres matchup includes our prediction, picks and the latest betting odds.

Before making any Diamondbacks vs. Padres picks, be sure to check out the latest MLB predictions and betting advice from Dimers Pro.

Conclusion

We predict the Diamondbacks, with a 52% win probability, will likely beat the Padres on Thursday.

AI and automation have enhanced this article to quickly deliver accurate Diamondbacks vs. Padres insights, with human oversight ensuring high editorial quality. Our predictions are drawn from up-to-date data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

Note: Clicking links to our partners may earn us a referral fee. Learn about how we review products and services.

More on MLB

Stay up-to-date with the latest MLB news and MLB parlay picks throughout the season. Plus, our World Series odds provide the most up-to-date probabilities for the World Series, American League, National League and each division.

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Written by
Dave Garofolo
Content Producer

Dave Garofolo uses sophisticated AI-driven analytics to make predictions and evaluate player performances in the NBA, MLB, NFL, NHL, NCAAM, and PGA TOUR tournaments, crafting insightful game and prop previews.

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