Arizona Cardinals vs. Seattle Seahawks updated prediction featuring Emari Demercado, Jaxon Smith-Njigba [Week 10, 2025]

Dimers' latest NFL predictions are live for Seattle Seahawks and Arizona Cardinals in Week 10, with our model giving the Seahawks a 73% of winning against the Cardinals on Sunday.

This update builds on our early Seahawks-Cardinals predictions, delivering refreshed win probabilities, score projections, and TD predictions for Emari Demercado, Jaxon Smith-Njigba, and more.

For the most accurate simulation-based insights—including spread and total picks, touchdown probabilities, and the full list of player props—head to our Cardinals vs. Seahawks page.

What's changed? Arizona vs. Seattle updated predictions

Our NFL predictions model has been re-run with the newest available data, creating a clearer picture of how this Cardinals vs. Seahawks matchup stacks up. Here are the updated forecasted:

• Straight Up Win Probabilities: Cardinals 27%, Seahawks 73%
• Predicted Final Score: Cardinals 19-25 Seahawks
• Spread: Cardinals (+6.5) 50%, Seahawks (-6.5) 50%
• Total Points (44.5): Over 53%, Under 47%

As of November 6, 2025, these Cardinals-Seahawks calculations reflect changes since our early-week simulation.

Anytime touchdown scorer predictions

New NFL player projections for Week 10 highlight the top candidates to find the end zone in Cardinals-Seahawks on Sunday:

Arizona Cardinals

• Emari Demercado: 35.1% probability
• Trey McBride: 33.3% probability
• Marvin Harrison: 32.4% probability

Seattle Seahawks

• Jaxon Smith-Njigba: 47.0% probability
• Zach Charbonnet: 46.3% probability
• Kenneth Walker: 39.0% probability

Cardinals vs. Seahawks latest odds

The best current odds from the top sportsbooks in the US:

• Spread: Cardinals +6.5 (+100), Seahawks -6.5 (-115)
• Moneyline: Cardinals +260, Seahawks -305
• Total: Over/Under 44.5 (-115/-105)

Odds are correct at time of publication and are subject to change—track live updates via our NFL odds page.

Cardinals vs. Seahawks Week 10 details

The NFL Week 10 game between the Seahawks and Cardinals at Lumen Field is scheduled for November 9, 2025.

• Who: Arizona Cardinals vs. Seattle Seahawks
• Date: Sunday, November 9, 2025
• Time: 4:05PM ET/1:05PM PT
• Venue: Lumen Field

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Conclusion

We predict the Seahawks, with a 73% win probability, will likely beat the Cardinals in Week 10 of the NFL season. Dimers.com will provide full game coverage closer to kickoff, so stay tuned for updates.

Enhanced by AI and automation, this article delivers quick, accurate insights on the Cardinals vs. Seahawks game, with human oversight maintaining high editorial quality. Our predictions are drawn from the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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