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Cardinals vs. Texans prediction: Houston favored to win in NFL Week 15 [2025]

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Written by Dave Garofolo

Get Arizona Cardinals vs Houston Texans predictions for NFL Sunday.

Arizona Cardinals-Houston Texans Predictions and Game Preview.
Arizona Cardinals vs. Houston Texans NFL prediction for Sunday, December 14, 2025.

The Houston Texans and Arizona Cardinals will meet in Week 15 of the NFL season at NRG Stadium on Sunday, starting at 1:00PM ET.

Based on the latest simulations, Dimers' advanced NFL model predicts the Texans as the most likely winner of the Cardinals vs. Texans game.

This article offers a closer look at Sunday's matchup, including projected touchdown scorers, best bets and player prop picks.

Cardinals vs. Texans prediction: Who will win and cover?

Since our Cardinals-Texans predictions earlier in the week, we have simulated the result of Sunday's NFL matchup between the Cardinals and Texans 10,000 times as part of our NFL predictions coverage.

Our independent predictive model currently gives the Texans an 83% chance of beating the Cardinals in Week 15 of the NFL season. Our predicted final score has the Texans winning 25-16.

According to our model, the Cardinals (+10.5) have a 54% chance of covering the spread, while the 42.5-point over/under has a 52% chance of staying under.

 

To see win probabilities for every matchup this week, check out our expert NFL Week 15 straight up picks.

Cardinals vs. Texans odds

We have researched the best NFL odds in America for this game, which are listed here:

Bet Type Cardinals Texans
Spread +10.5 (-110) -10.5 (-104)
Moneyline +455 -600
Total o42.5 (-108) u42.5 (-112)

All odds are correct at the time of publication and are subject to change.

Cardinals vs. Texans picks and best bet

After matching our predictions against the best current odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:

Bet Type Pick Bet Now
Spread Cardinals +10.5 -110
Moneyline Cardinals +455
Total Under 42.5 -112

According to our NFL best bets, the top play to make on this game is Cardinals +10.5 at the spread.

 

Cardinals vs. Texans TD scorers

Who will score a touchdown in Cardinals vs. Texans?

According to our list of touchdown scorer predictions for today, Woody Marks is most likely to score an anytime touchdown in Cardinals vs. Texans.

Our projections give Marks a 51.1% chance of scoring a TD at NRG Stadium, while the running back is a 14.8% chance of scoring the first touchdown the game.

Anytime touchdown scorer predictions

Arizona Cardinals

Player Anytime TD Probability
Bam Knight (RB) 39.1%
Trey McBride (TE) 36.0%
Michael Wilson (WR) 29.2%
Emari Demercado (RB) 23.0%
Jacoby Brissett (QB) 15.7%

Houston Texans

Player Anytime TD Probability
Woody Marks (RB) 51.1%
Nico Collins (WR) 40.5%
Jayden Higgins (WR) 31.2%
Dalton Schultz (TE) 21.1%
Christian Kirk (WR) 16.5%

First touchdown scorer predictions

Arizona Cardinals

Player First TD Probability
Bam Knight (RB) 7.6%
Trey McBride (TE) 6.9%
Michael Wilson (WR) 5.3%
Emari Demercado (RB) 4.0%
Jacoby Brissett (QB) 2.6%

Houston Texans

Player First TD Probability
Woody Marks (RB) 14.8%
Nico Collins (WR) 10.7%
Jayden Higgins (WR) 7.7%
Dalton Schultz (TE) 4.9%
Christian Kirk (WR) 3.7%

Cardinals vs Texans player props

Discover our predictions for the players likely to lead in passing, rushing and receiving yards for both the Cardinals and Texans. Head to our NFL player projections page now to access a full list of player prop projections for every offensive player in this matchup and all other Week 15 games.

Quarterbacks

Of the starting quarterbacks, the Cardinals' Jacoby Brissett is projected for 237 passing yards, while the Texans' C.J. Stroud is expected to throw for 239 yards.

Player Proj. Pass Yards
Jacoby Brissett (ARI) 237
C.J. Stroud (HOU) 239

Cardinals rushing

Player Proj. Rush Yards
Bam Knight 34
Jacoby Brissett 17
Michael Carter 17

Texans rushing

Player Proj. Rush Yards
Woody Marks 82
C.J. Stroud 14
Dare Ogunbowale 14

Cardinals receiving

Player Proj. Rec. Yards
Michael Wilson 70
Trey McBride 65
Andre Baccellia 20
Jalen Brooks 18
Bam Knight 16

Texans receiving

Player Proj. Rec. Yards
Nico Collins 79
Jayden Higgins 43
Dalton Schultz 42
Christian Kirk 22
Xavier Hutchinson 19

Cardinals vs. Texans game-day updates and essential details

The NFL Week 15 action between the Texans and Cardinals at NRG Stadium is scheduled to begin at 1:00PM ET.

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Conclusion

We predict the Texans, with an 83% win probability, will likely beat the Cardinals in Week 15 of the NFL season.

AI and automation have enhanced this article to quickly deliver accurate Cardinals vs. Texans insights, with human oversight ensuring high editorial quality. Our predictions are drawn from the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

Note: Clicking links to our partners may earn us a referral fee. Learn about how we review products and services.

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Written by
Dave Garofolo
Content Producer

Dave Garofolo uses sophisticated AI-driven analytics to make predictions and evaluate player performances in the NBA, MLB, NFL, NHL, NCAAM, and PGA TOUR tournaments, crafting insightful game and prop previews.

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