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Cardinals vs. Bengals prediction: Why Cincinnati is favored to win in NFL Week 17 [2025]

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Written by Ryan Leaver

Get Arizona Cardinals vs Cincinnati Bengals predictions for NFL Sunday.

Arizona Cardinals-Cincinnati Bengals Predictions and Game Preview.
Arizona Cardinals vs. Cincinnati Bengals NFL prediction for Sunday, December 28, 2025.

The Cincinnati Bengals will take on the Arizona Cardinals in NFL Week 17 action at Paycor Stadium on Sunday, starting at 1:00 PM ET.

Based on updated simulations, Dimers' advanced NFL model projects the Bengals as the most likely winner of the Cardinals vs. Bengals game.

This article offers further insights into Sunday's matchup, including projected touchdown scorers, best bets and player prop picks.

Cardinals vs. Bengals prediction: Who will win and cover?

Since our Cardinals-Bengals predictions earlier in the week, we have simulated the result of Sunday's NFL game between the Cardinals and Bengals 10,000 times as part of our NFL predictions coverage.

Our famous predictive model currently gives the Bengals a 72% chance of defeating the Cardinals in Week 17 of the NFL season. Our predicted final score has the Bengals winning 30-23.

According to our model, the bookmakers have got it right, and the Cardinals and Bengals each have a 50% chance of covering the spread, while the 53.5-point over/under also has an equal 50-50 chance of hitting.

 

To see win probabilities for every matchup this week, check out our expert NFL Week 17 straight up picks.

Cardinals vs. Bengals odds

We have sourced the best NFL odds in America for this game, which are listed here:

Bet Type Cardinals Bengals
Spread +7 (-110) -7 (-108)
Moneyline +280 -320
Total o53.5 (-110) u53.5 (-108)

All odds are correct at the time of publication and are subject to change.

Cardinals vs. Bengals picks and best bet

After matching our predictions against the best current odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:

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Written by
Ryan Leaver
Senior Sports and Betting Editor

Ryan Leaver uses advanced statistical models and simulations to predict outcomes and provide predictions for the NBA, NFL, college football, college basketball, and soccer. He offers detailed game previews, best bets, props, and futures articles.

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