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American University vs. Loyola (MD) prediction: American University favored to win men's college basketball matchup [1/28/2026]

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Written by Mac Douglass

Get American University vs Loyola (MD) predictions for college basketball Wednesday.

American University-Loyola (MD) Predictions and Game Preview.
American University vs. Loyola (MD) men's college basketball prediction for Wednesday, January 28, 2026.

Loyola (MD) will face American University in men's college basketball action at Reitz Arena on Wednesday, starting at 7:00 PM ET.

Based on the latest simulations, Dimers' proven college basketball model predicts American University as the most likely winner of the American University vs. Loyola (MD) game.

This article offers a closer look at Wednesday's matchup, including an expanded look at the predicted score, best bets and picks.

American University vs. Loyola (MD) prediction: Who will win and cover?

Using innovative machine learning and statistical analysis, we have simulated the outcome of Wednesday's NCAA basketball matchup between American University and Loyola (MD) 10,000 times as part of our men's college basketball predictions coverage.

Our leading predictive model currently gives American University a 63% chance of defeating Loyola (MD). Our predicted final score has American University winning 75-71.

According to our model, the bookmakers have got it right, and American University and Loyola (MD) each have a 50% chance of covering the spread, while the 147.5-point over/under has a 51% chance of staying under.

 

American University vs. Loyola (MD) odds

We have sourced the best men's college basketball odds in America for this game, which are listed here:

Bet Type American University Loyola (MD)
Spread -3.5 (-105) +3.5 (-108)
Moneyline -170 +150
Total o147.5 (-110) u147.5 (-108)

All odds are correct at the time of publication and are subject to change.

American University vs. Loyola (MD) picks and best bet

After matching our predictions against the best current odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:

Bet Type Pick Bet Now
Spread Loyola (MD) +3.5 -108
Moneyline American University -170
Total Under 147.5 -108

According to our men's college basketball best bets, the top play to make on this game is American University to win.

 

American University vs. Loyola (MD) game-day updates and essential details

Wednesday's men's college basketball action between Loyola (MD) and American University at Reitz Arena is scheduled to start at 7:00 PM ET.

  • Who: American University vs. Loyola (MD)
  • Date: Wednesday, January 28, 2026
  • Time: 7:00 PM ET/4:00PM PT
  • Venue: Reitz Arena

Conclusion

We predict American University, with a 63% win probability, will likely beat Loyola (MD) on Wednesday.

AI and automation have enhanced this article to quickly deliver accurate American University vs. Loyola (MD) insights, with human oversight ensuring high editorial quality. Our predictions are sourced from the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

Note: Clicking links to our partners may earn us a referral fee. Learn about how we review products and services.

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Written by
Mac Douglass
Senior Editor

Mac Douglass specializes in NFL previews for the NFC South and NFC East, MLB best bets, Formula 1 race previews, and professional tennis insights. Combining predictive simulations and data-driven sports analysis, Mac provides in-depth content to elevate the betting experience for sports fans.

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