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American University vs. Holy Cross prediction: American University favored to win men's college basketball matchup [1/24/2026]

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Written by Dave Garofolo

Get American University vs Holy Cross predictions for college basketball Saturday.

American University-Holy Cross Predictions and Game Preview.
American University vs. Holy Cross men's college basketball prediction for Saturday, January 24, 2026.

Holy Cross will face the favored American University in men's college basketball action at Hart Center on Saturday, commencing at 12:00 PM ET.

Based on the latest simulation results, Dimers' advanced college basketball model projects American University as the most likely winner of the American University vs. Holy Cross game.

This article offers a closer look at Saturday's matchup, including an expanded look at the predicted score, best bets and picks.

American University vs. Holy Cross prediction: Who will win and cover?

Using innovative machine learning and data, we have simulated the outcome of Saturday's NCAA basketball game between American University and Holy Cross 10,000 times as part of our men's college basketball predictions coverage.

Our leading predictive model gives American University a 66% chance of beating Holy Cross. Our predicted final score has American University winning 71-67.

According to our model, Holy Cross (+4.5) has a 53% chance of covering the spread, while the over/under total of 139.5 points has a 52% chance of staying under.

 

American University vs. Holy Cross odds

We have researched the best men's college basketball odds in America for this game, which are listed here:

Bet Type American University Holy Cross
Spread -4.5 (-108) +4.5 (-105)
Moneyline -218 +198
Total o139.5 (-105) u139.5 (-114)

All odds are correct at the time of publication and are subject to change.

American University vs. Holy Cross picks and best bet

After matching our predictions against the best available odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:

Bet Type Pick Bet Now
Spread Holy Cross +4.5 -105
Moneyline Holy Cross +198
Total Under 139.5 -114

According to our men's college basketball best bets, the top play to make on this game is Holy Cross +4.5 at the spread.

 

American University vs. Holy Cross game-day updates and essential details

Saturday's men's college basketball game between Holy Cross and American University at Hart Center is scheduled to begin at 12:00 PM ET.

  • Who: American University vs. Holy Cross
  • Date: Saturday, January 24, 2026
  • Time: 12:00 PM ET/9:00AM PT
  • Venue: Hart Center

Conclusion

We predict American University, with a 66% win probability, will likely beat Holy Cross on Saturday.

AI and automation have enhanced this article to quickly deliver accurate American University vs. Holy Cross insights, with human oversight ensuring high editorial quality. Our predictions are sourced from the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

Note: Clicking links to our partners may earn us a referral fee. Learn about how we review products and services.

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Written by
Dave Garofolo
Content Producer

Dave Garofolo uses sophisticated AI-driven analytics to make predictions and evaluate player performances in the NBA, MLB, NFL, NHL, NCAAM, and PGA TOUR tournaments, crafting insightful game and prop previews.

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