Xavier vs. Marquette prediction: Why Marquette is favored to win men's college basketball matchup [3/11/2026]

Marquette and Xavier will meet in men's college basketball action at Madison Square Garden on Wednesday, with tipoff at 6:30 PM ET.

Based on updated simulations, Dimers' advanced college basketball model predicts Marquette as the most likely winner of the Xavier vs. Marquette game.

This article offers an expanded analysis of Wednesday's matchup, including an expanded look at the predicted score, best bets and picks.

Xavier vs. Marquette prediction: Who will win and cover?

Using trusted machine learning and data analysis, we have simulated the outcome of Wednesday's NCAA basketball matchup between Xavier and Marquette 10,000 times as part of our men's college basketball predictions coverage.

Our leading predictive model currently gives Marquette a 64% chance of beating Xavier. Our predicted final score has Marquette winning 78-74.

According to our model, Xavier (+3.5) has a 55% chance of covering the spread, while the over/under total of 157.5 points has a 55% chance of staying under.

Xavier vs. Marquette odds

We have sourced the best men's college basketball odds in America for this game, which are listed here:

Bet Type	Xavier	Marquette
Spread	+3.5 (-102)	-3.5 (-120)
Moneyline	+158	-180
Total	o157.5 (-110)	u157.5 (-108)

All odds are correct at the time of publication and are subject to change.

Xavier vs. Marquette picks and best bet

After matching our predictions against the best available odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:

Bet Type	Pick	Bet Now
Spread	Xavier +3.5	-102
Moneyline	Marquette	-180
Total	Under 157.5	-108

According to our men's college basketball best bets, the top play to make on this game is Xavier +3.5 at the spread.

These picks are based on our probabilities matched against the implied probabilities from the sportsbook odds.

Xavier vs. Marquette game-day updates and essential details

Wednesday's men's college basketball matchup between Marquette and Xavier at Madison Square Garden is scheduled to start at 6:30 PM ET.

• Who: Xavier vs. Marquette
• Date: Wednesday, March 11, 2026
• Time: 6:30 PM ET/3:30PM PT
• Venue: Madison Square Garden

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Conclusion

We predict Marquette, with a 64% win probability, will likely beat Xavier on Wednesday.

AI and automation have enhanced this article to quickly deliver accurate Xavier vs. Marquette insights, with human oversight ensuring high editorial quality. Our predictions are drawn from the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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