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Xavier vs. DePaul prediction: DePaul favored to win NCAAW matchup [2/22/2026]
Updated: | First published:
Written by Ryan Leaver, Senior Sports and Betting Editor
Get Xavier vs DePaul predictions for college basketball Sunday.
DePaul will square off with Xavier in women's college basketball action at Wintrust Arena on Sunday, starting at 3:00 PM ET.
Based on updated simulations, Dimers' new women's basketball model predicts DePaul as the most likely winner of the Xavier vs. DePaul game.
This article offers an expanded analysis of Sunday's matchup, including best bets and picks.
Xavier vs. DePaul prediction: Who will win?
Using innovative machine learning and data analysis, we have simulated the outcome of Sunday's women's basketball game between Xavier and DePaul 10,000 times as part of our women's college basketball predictions coverage.
Our independent predictive model currently gives DePaul a 79% chance of defeating Xavier.
According to our model, the 127.5-point over/under has a 52% chance of going over.
Xavier vs. DePaul odds
We have researched the best women's college basketball odds in America for this game, which are listed here:
| Bet Type | Xavier | DePaul |
|---|---|---|
| Spread | +2.5 (-110) | -2.5 (-110) |
| Moneyline | +124 | -148 |
| Total | o127.5 (-110) | u127.5 (-110) |
All odds are correct at the time of publication and are subject to change.
Xavier vs. DePaul picks and best bet
After matching our probabilities against the best current odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:
| Bet Type | Pick | Bet Now |
|---|---|---|
| Spread | DePaul -2.5 | -110 |
| Moneyline | DePaul | -148 |
| Total | Over 127.5 | -110 |
According to our women's college basketball best bets, the top play to make on this game is DePaul to win.
These picks are based on our probabilities matched against the implied probabilities from the sportsbook odds.
Xavier vs. DePaul game-day updates and essential details
Sunday's women's basketball matchup between DePaul and Xavier at Wintrust Arena is scheduled to commence at 3:00 PM ET.
- Who: Xavier vs. DePaul
- Date: Sunday, February 22, 2026
- Time: 3:00 PM ET/12:00PM PT
- Venue: Wintrust Arena
Conclusion
We predict DePaul, with a 79% win probability, will likely beat Xavier on Sunday.
AI and automation have enhanced this article to quickly deliver accurate Xavier vs. DePaul insights, with human oversight ensuring high editorial quality. Our predictions are drawn from the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.
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Ryan Leaver uses advanced statistical models and simulations to predict outcomes and provide predictions for the NBA, NFL, college football, college basketball, and soccer. He offers detailed game previews, best bets, props, and futures articles.
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