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Wyoming vs. Grand Canyon prediction: Grand Canyon favored to win men's college basketball matchup [2/21/2026]
Updated: | First published:
Written by Dave Garofolo, Content Producer
Get Wyoming vs Grand Canyon predictions for college basketball Saturday.
Men's college basketball action continues on Saturday at 8:00 PM ET as Wyoming takes on Grand Canyon in men's college basketball action at Global Credit Union Arena.
Based on the latest simulations, Dimers' advanced college basketball model projects Grand Canyon as the most likely winner of the Wyoming vs. Grand Canyon game.
This article offers a closer look at Saturday's matchup, including an expanded look at the predicted score, best bets and picks.
Wyoming vs. Grand Canyon prediction: Who will win and cover?
Using trusted machine learning and data, we have simulated the outcome of Saturday's NCAA basketball matchup between Wyoming and Grand Canyon 10,000 times as part of our men's college basketball predictions coverage.
Our independent predictive model gives Grand Canyon a 79% chance of beating Wyoming. Our predicted final score has Grand Canyon winning 78-69.
According to our model, the bookies have got it right, and Wyoming and Grand Canyon each have a 50% chance of covering the spread, while the 147.5-point over/under has a 57% chance of going over.
Wyoming vs. Grand Canyon odds
We have researched the best men's college basketball odds in America for this game, which are listed here:
| Bet Type | Wyoming | Grand Canyon |
|---|---|---|
| Spread | +8.5 (-115) | -8.5 (-105) |
| Moneyline | +300 | -375 |
| Total | o147.5 (-118) | u147.5 (-114) |
All odds are correct at the time of publication and are subject to change.
Wyoming vs. Grand Canyon picks and best bet
After matching our predictions against the best current odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:
| Bet Type | Pick | Bet Now |
|---|---|---|
| Spread | Grand Canyon -8.5 | -105 |
| Moneyline | Grand Canyon | -375 |
| Total | Over 147.5 | -118 |
According to our men's college basketball best bets, the top play to make on this game is Over 147.5 total points.
These picks are based on our probabilities matched against the implied probabilities from the sportsbook odds.
Wyoming vs. Grand Canyon game-day updates and essential details
Saturday's men's college basketball game between Grand Canyon and Wyoming at Global Credit Union Arena is scheduled to start at 8:00 PM ET.
- Who: Wyoming vs. Grand Canyon
- Date: Saturday, February 21, 2026
- Time: 8:00 PM ET/5:00PM PT
- Venue: Global Credit Union Arena
Conclusion
We predict Grand Canyon, with a 79% win probability, will likely beat Wyoming on Saturday.
AI and automation have enhanced this article to quickly deliver accurate Wyoming vs. Grand Canyon insights, with human oversight ensuring high editorial quality. Our predictions are sourced from the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.
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Dave Garofolo uses sophisticated AI-driven analytics to make predictions and evaluate player performances in the NBA, MLB, NFL, NHL, NCAAM, and PGA TOUR tournaments, crafting insightful game and prop previews.
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