Women's college basketball picks today: Sunday's best bets include USC vs. California play [12/21/2025]

Today’s women's college basketball picks for December 21, 2025 are here, with USC vs. California among the top plays identified by our model across Sunday’s women's basketball play.

Dimers’ predictive analytics engine runs 24/7, scanning the latest women's basketball odds to uncover top betting edges. The result? Data-backed picks that help Dimers Pro members make smarter decisions.

List of NCAAW picks tonight [12/21, updated 7:02PM ET]

Below, you’ll find today’s best women's college basketball bets, ranked by edge for Sunday, December 21, 2025.

USC ML (-752)

• Edge: 5.9%
• Probability: 94.2%
• Matchup: USC vs. California (8:30PM ET, Sunday)

Our model has identified value on USC to defeat California at -752 odds. A 94.2% probability produces an edge of 5.9%, making this the strongest play for today's women's college basketball slate.

USC -12.5 (-110)

• Edge: 4.2%
• Probability: 56.6%
• Matchup: USC vs. California (8:30PM ET, Sunday)

USC -12.5 carries a 4.2% edge and a probability of 56.6% at -110 odds, according to our model.

USC vs. California over 129.5 points (-110)

• Edge: 3.1%
• Probability: 55.5%
• Matchup: USC vs. California (8:30PM ET, Sunday)

USC vs. California over 129.5 points at -110 odds shows a 3.1% edge, supported by a 55.5% probability in simulations.

NCAAW best bets summary: Sunday, 12/21/2025

As of 7:02PM ET, here are our top women's college basketball bets by edge recommended by our model:

List of upcoming women's college basketball games to bet on now

• Old Dominion vs. Ole Miss (7:30PM ET, Sunday)
• USC vs. California (8:30PM ET, Sunday)

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Conclusion

Our women's college basketball best bets are locked and loaded for December 21, 2025, featuring plays such as USC ML and USC -12.5. Powered by advanced simulations, these picks are here to boost your betting game.

This article, enhanced by AI and automation, aims to deliver accurate college basketball insights quickly, with human oversight ensuring high editorial quality. Our predictions are rooted in current data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

All odds and probabilities in this article are correct and accurate at the time of publication.

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