Women's college basketball picks today: Monday's best bets include Michigan State vs. Ole Miss play [12/22/2025]

Today’s women's college basketball picks for December 22, 2025 are here, with Michigan State vs. Ole Miss and Western Michigan vs. Ohio State among the top plays identified by our model across Monday’s women's basketball play.

Dimers’ predictive analytics engine runs 24/7, searching the latest women's basketball odds to find top betting edges. The result? Data-backed picks that help Dimers Pro members make smarter decisions.

List of NCAAW picks today [12/22, updated 6:03PM ET]

Below, you’ll find today’s best women's college basketball bets, ranked by edge for Monday, December 22, 2025.

Ole Miss ML (-142)

• Edge: 11.9%
• Probability: 70.5%
• Matchup: Michigan State vs. Ole Miss (7:30PM ET, Monday)

Our model has identified value on Ole Miss to defeat Michigan State at -142 odds. A 70.5% probability produces an edge of 11.9%, making this the strongest play for today's women's college basketball slate.

Western Michigan +43.5 (-114)

• Edge: 6.7%
• Probability: 60%
• Matchup: Western Michigan vs. Ohio State (6:30PM ET, Monday)

Western Michigan +43.5 carries a 6.7% edge and a probability of 60% at -114 odds, according to our model.

Western Michigan vs. Ohio State over 136.5 points (-114)

• Edge: 4.9%
• Probability: 58.1%
• Matchup: Western Michigan vs. Ohio State (6:30PM ET, Monday)

Western Michigan vs. Ohio State over 136.5 points at -114 odds shows a 4.9% edge, supported by a 58.1% probability in simulations.

Southern Indiana vs. Tennessee over 143.5 points (-105)

• Edge: 4.3%
• Probability: 55.6%
• Matchup: Southern Indiana vs. Tennessee (6:30PM ET, Monday)

A 4.3% edge and 55.6% probability make Southern Indiana vs. Tennessee over 143.5 points at a value play in the Southern Indiana vs. Tennessee matchup, per our model.

Ole Miss -2.5 (-110)

• Edge: 4.1%
• Probability: 56.5%
• Matchup: Michigan State vs. Ole Miss (7:30PM ET, Monday)

Ole Miss -2.5 at -110 odds presents a 4.1% edge, with simulations resulting in a probability of 56.5%.

NCAAW best bets summary: Monday, 12/22/2025

As of 6:03PM ET, here are our top women's college basketball bets by edge recommended by our model:

Matchup	Bet	Odds	Edge	Probability
Michigan State vs. Ole Miss	Ole Miss ML	-142 @ DraftKings	11.9%	70.5%
Western Michigan vs. Ohio State	Western Michigan +43.5	-114 @ FanDuel	6.7%	60%
Western Michigan vs. Ohio State	Over 136.5 Points	-114 @ FanDuel	4.9%	58.1%
Southern Indiana vs. Tennessee	Over 143.5 Points	-105 @ DraftKings	4.3%	55.6%
Michigan State vs. Ole Miss	Ole Miss -2.5	-110 @ DraftKings	4.1%	56.5%

List of upcoming women's college basketball games to bet on now

• Western Michigan vs. Ohio State (6:30PM ET, Monday)
• Southern Indiana vs. Tennessee (6:30PM ET, Monday)
• Michigan State vs. Ole Miss (7:30PM ET, Monday)

What Is Dimebot?

Dimebot is Dimers’ AI bet assistant, designed to surface swift insights, answer betting questions, and help you explore data more efficiently.

Conclusion

Our women's college basketball best bets are locked and loaded for December 22, 2025, featuring plays such as Ole Miss ML and Western Michigan +43.5. Powered by advanced simulations, these picks are here to boost your betting game.

This article, enhanced by AI and automation, aims to deliver accurate college basketball insights quickly, with human oversight ensuring high editorial quality. Our predictions are sourced from current data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

All odds and probabilities in this article are correct and accurate at the time of publication.

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