Western Kentucky vs. Southern Miss prediction: Southern Miss favored to win New Orleans Bowl [2025]

Southern Miss and Western Kentucky will meet in the 2025 New Orleans Bowl at Caesars Superdome on Tuesday, commencing at 5:30 PM ET.

Based on updated simulations, Dimers' proven college football model gives Southern Miss a slight edge with a 53% win probability over Western Kentucky.

This article offers an expanded analysis of Tuesday's Western Kentucky vs. Southern Miss matchup, including an expanded look at the predicted score, best bets and picks.

New Orleans Bowl prediction: Who will win and cover?

Using innovative machine learning and data, we have simulated the outcome of the 2025 New Orleans Bowl 10,000 times as part of our college football predictions coverage.

Our independent predictive model gives Southern Miss a 53% chance of beating Western Kentucky. Our predicted final score has Southern Miss winning 28-27.

According to our model, Southern Miss (+1.5) has a 55% chance of covering the spread, while the 58.5-point over/under has a 60% chance of going over.

New Orleans Bowl odds

We have sourced the best college football odds in America for this game, which are listed here:

All odds are correct at the time of publication and are subject to change.

Western Kentucky vs. Southern Miss picks and best bet

After matching our predictions against the best current odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below: