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Western Kentucky vs. Southern Miss prediction: Southern Miss favored to win New Orleans Bowl [2025]
Get Western Kentucky vs Southern Miss predictions for college football Tuesday.

Southern Miss and Western Kentucky will meet in the 2025 New Orleans Bowl at Caesars Superdome on Tuesday, beginning at 5:30 PM ET.
Based on the latest simulation results, Dimers' advanced college football model predicts Southern Miss as the most likely winner of the Western Kentucky vs. Southern Miss game.
This article offers further insights into Tuesday's matchup, including an expanded look at the predicted score, best bets and picks.
New Orleans Bowl prediction: Who will win and cover?
Using innovative machine learning and data analysis, we have simulated the outcome of the 2025 New Orleans Bowl 10,000 times as part of our college football predictions coverage.
Our famous predictive model gives Southern Miss a 58% chance of beating Western Kentucky. Our predicted final score has Southern Miss winning 29-26.
According to our model, Southern Miss (-3) has a 53% chance of covering the spread, while the 58.5-point over/under has a 60% chance of going over.
New Orleans Bowl odds
We have researched the best college football odds in America for this game, which are listed here:
| Bet Type | Western Kentucky | Southern Miss |
|---|---|---|
| Spread | +3 (-110) | -3 (-102) |
| Moneyline | +120 | -142 |
| Total | o58.5 (-115) | u58.5 (-105) |
All odds are correct at the time of publication and are subject to change.
Western Kentucky vs. Southern Miss picks and best bet
After matching our predictions against the best current odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:
| Bet Type | Pick | Bet Now |
|---|---|---|
| Spread | Southern Miss -3 | -102 |
| Moneyline | Southern Miss | -142 |
| Total | Over 58.5 | -115 |
According to our college football best bets, the top play to make on this game is Over 58.5 total points.
Western Kentucky vs. Southern Miss game-day updates and essential details
Tuesday's college football matchup between Southern Miss and Western Kentucky at Caesars Superdome is scheduled to begin at 5:30 PM ET.
- Who: Western Kentucky vs. Southern Miss
- Date: Tuesday, December 23, 2025
- Time: 5:30 PM ET/2:30PM PT
- Venue: Caesars Superdome
Conclusion
We predict Southern Miss, with a 58% win probability, will likely beat Western Kentucky on Tuesday.
AI and automation have enhanced this article to quickly deliver accurate Western Kentucky vs. Southern Miss insights, with human oversight ensuring high editorial quality. Our predictions are based on up-to-date data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.
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