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Virginia Tech vs. Louisville prediction: Louisville favored to win women's college basketball matchup [1/4/2026]
Updated: | First published:
Written by Ryan Leaver, Senior Sports and Betting Editor
Get Virginia Tech vs Louisville predictions for college basketball Sunday.
Louisville and Virginia Tech are scheduled to meet in the women's college basketball at KFC Yum! Center on Sunday, with tipoff at 4:00 PM ET.
Based on updated simulation results, Dimers' new women's basketball model projects Louisville as the most likely winner of the Virginia Tech vs. Louisville game.
This article offers a closer look at Sunday's matchup, including best bets and picks.
Virginia Tech vs. Louisville prediction: Who will win?
Using innovative machine learning and data, we have simulated the outcome of Sunday's women's basketball matchup between Virginia Tech and Louisville 10,000 times as part of our women's college basketball predictions coverage.
Our famous predictive model gives Louisville a 91% chance of defeating Virginia Tech.
According to our model, the over/under total of 140.5 points has a 51% chance of going over.
Virginia Tech vs. Louisville odds
We have sourced the best women's college basketball odds in America for this game, which are listed here:
| Bet Type | Virginia Tech | Louisville |
|---|---|---|
| Spread | +16.5 (-110) | -16.5 (-110) |
| Moneyline | +1260 | -2083 |
| Total | o140.5 (-110) | u140.5 (-110) |
All odds are correct at the time of publication and are subject to change.
Virginia Tech vs. Louisville picks and best bet
After matching our probabilities against the best available odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:
| Bet Type | Pick | Bet Now |
|---|---|---|
| Spread | Virginia Tech +16.5 | -110 |
| Moneyline | Virginia Tech | +1260 |
| Total | Over 140.5 | -110 |
According to our women's college basketball best bets, the top play to make on this game is Virginia Tech to win.
Virginia Tech vs. Louisville game-day updates and essential details
Sunday's women's basketball matchup between Louisville and Virginia Tech at KFC Yum! Center is scheduled to begin at 4:00 PM ET.
- Who: Virginia Tech vs. Louisville
- Date: Sunday, January 4, 2026
- Time: 4:00 PM ET/1:00PM PT
- Venue: KFC Yum! Center
Conclusion
We predict Louisville, with a 91% win probability, will likely beat Virginia Tech on Sunday.
AI and automation have enhanced this article to quickly deliver accurate Virginia Tech vs. Louisville insights, with human oversight ensuring high editorial quality. Our predictions are based on up-to-date data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.
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Ryan Leaver uses advanced statistical models and simulations to predict outcomes and provide predictions for the NBA, NFL, college football, college basketball, and soccer. He offers detailed game previews, best bets, props, and futures articles.
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