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Vermont vs. Louisville prediction: Louisville favored to win women's March Madness First Round matchup [3/21/2026]
Updated: | First published:
Written by Ryan Leaver, Senior Sports and Betting Editor
Get Vermont vs Louisville predictions for college basketball Saturday.
Louisville will take on Vermont in March Madness First Round action at KFC Yum! Center on Saturday, beginning at 12:00 PM ET.
Based on the latest simulation results, Dimers' new women's basketball model projects Louisville as the most likely winner of the Vermont vs. Louisville game.
This article offers further insights into Saturday's matchup, including best bets and picks.
Vermont vs. Louisville prediction: Who will win and advance to the Second Round?
Using innovative machine learning and statistical analysis, we have simulated the outcome of Saturday's NCAAW Tournament game between Vermont and Louisville 10,000 times as part of our women's college basketball predictions coverage.
Our famous predictive model gives Louisville a 97% chance of beating Vermont.
According to our model, the over/under total of 121.5 points has a 51% chance of staying under.
Vermont vs. Louisville odds
We have researched the best women's college basketball odds in America for this game, which are listed here:
| Bet Type | Vermont | Louisville |
|---|---|---|
| Spread | +27.5 (-110) | -27.5 (-110) |
| Moneyline | +5000 | -20000 |
| Total | o121.5 (-110) | u121.5 (-110) |
All odds are correct at the time of publication and are subject to change.
Vermont vs. Louisville picks and best bet
After matching our probabilities against the best current odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:
| Bet Type | Pick | Bet Now |
|---|---|---|
| Spread | Vermont +27.5 | -110 |
| Moneyline | Vermont | +5000 |
| Total | Under 121.5 | -110 |
According to our women's college basketball best bets, the top play to make on this game is Vermont to win.
These picks are based on our probabilities matched against the implied probabilities from the sportsbook odds.
Vermont vs. Louisville game-day updates and essential details
Saturday's women's basketball matchup between Louisville and Vermont at KFC Yum! Center is scheduled to commence at 12:00 PM ET.
- Who: Vermont vs. Louisville
- Date: Saturday, March 21, 2026
- Time: 12:00 PM ET/9:00AM PT
- Venue: KFC Yum! Center
- March Madness stage: First Round
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Conclusion
We predict Louisville, with a 97% win probability, will likely beat Vermont this women's March Madness First Round matchup.
AI and automation have enhanced this article to quickly deliver accurate Vermont vs. Louisville insights, with human oversight ensuring high editorial quality. Our predictions are drawn from the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.
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Ryan Leaver uses advanced statistical models and simulations to predict outcomes and provide predictions for the NBA, NFL, college football, college basketball, and soccer. He offers detailed game previews, best bets, props, and futures articles.
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