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UC San Diego vs. UC Irvine prediction: UC Irvine favored to win men's college basketball matchup [2/21/2026]
Updated: | First published:
Written by Dave Garofolo, Content Producer
Get UC San Diego vs UC Irvine predictions for college basketball Saturday.
Men's college basketball action continues on Saturday at 10:00 PM ET as UC San Diego takes on UC Irvine in men's college basketball action at Bren Events Center.
Based on the latest simulations, Dimers' advanced college basketball model projects UC Irvine as the most likely winner of the UC San Diego vs. UC Irvine game.
This article offers a closer look at Saturday's matchup, including an expanded look at the predicted score, best bets and picks.
UC San Diego vs. UC Irvine prediction: Who will win and cover?
Using powerful machine learning and data analysis, we have simulated the result of Saturday's NCAA basketball game between UC San Diego and UC Irvine 10,000 times as part of our men's college basketball predictions coverage.
Our leading predictive model currently gives UC Irvine a 65% chance of beating UC San Diego. Our predicted final score has UC Irvine winning 75-71.
According to our model, UC San Diego (+3.5) has a 55% chance of covering the spread, while the 143.5-point over/under has a 54% chance of going over.
UC San Diego vs. UC Irvine odds
We have sourced the best men's college basketball odds in America for this game, which are listed here:
| Bet Type | UC San Diego | UC Irvine |
|---|---|---|
| Spread | +3.5 (-110) | -3.5 (-110) |
| Moneyline | +145 | -125 |
| Total | o143.5 (-110) | u143.5 (-110) |
All odds are correct at the time of publication and are subject to change.
UC San Diego vs. UC Irvine picks and best bet
After matching our probabilities against the best available odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:
| Bet Type | Pick | Bet Now |
|---|---|---|
| Spread | UC San Diego +3.5 | -110 |
| Moneyline | UC Irvine | -125 |
| Total | Over 143.5 | -110 |
According to our best men's college basketball bets, the top play to make on this game is UC Irvine to win.
These picks are based on our probabilities matched against the implied probabilities from the sportsbook odds.
UC San Diego vs. UC Irvine game-day updates and essential details
Saturday's men's college basketball action between UC Irvine and UC San Diego at Bren Events Center is scheduled to start at 10:00 PM ET.
- Who: UC San Diego vs. UC Irvine
- Date: Saturday, February 21, 2026
- Time: 10:00 PM ET/7:00PM PT
- Venue: Bren Events Center
Conclusion
We predict UC Irvine, with a 65% win probability, will likely beat UC San Diego on Saturday.
AI and automation have enhanced this article to quickly deliver accurate UC San Diego vs. UC Irvine insights, with human oversight ensuring high editorial quality. Our predictions are drawn from the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.
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Dave Garofolo uses sophisticated AI-driven analytics to make predictions and evaluate player performances in the NBA, MLB, NFL, NHL, NCAAM, and PGA TOUR tournaments, crafting insightful game and prop previews.
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