Rays vs. Blue Jays prediction: Why Toronto is favored to win Wednesday's MLB matchup [7/22/2026]
Get Tampa Bay Rays vs Toronto Blue Jays predictions for MLB Wednesday.

The Toronto Blue Jays and Tampa Bay Rays will meet in MLB action at Rogers Centre on Wednesday, starting at 7:07 PM ET.
The Blue Jays will send Braydon Fisher (3-3, 3.65 ERA) to the mound, while the Rays have opted for Griffin Jax (5-7, 4.08 ERA).
Based on updated simulations, Dimers' advanced MLB model gives the Blue Jays a slight edge with a 53.2% win probability over the Rays.
This article offers further insights into Wednesday's Rays vs. Blue Jays matchup, including best bets and picks.
Rays vs. Blue Jays prediction: Who will win and cover?
Our independent predictive model currently gives the Blue Jays a 53.2% chance of beating the Rays.
According to our model, the Blue Jays (+1.5) have a 64.3% chance of covering the run line, while the 8.5-run over/under has a 53.4% chance of going over,.
Rays vs. Blue Jays odds [7/22/2026]
We have sourced the best MLB odds in America for this game, which are listed here:
| Bet Type | Rays | Blue Jays |
|---|---|---|
| Run Line | -1.5 (+158) | +1.5 (-174) |
| Moneyline | +100 | -104 |
| Total | o8.5 (-104) | u8.5 (+100) |
All odds are correct at the time of publication and are subject to change.
Rays vs. Blue Jays picks and best bet
After matching our predictions against the best available odds, we can reveal our picks for each of the major markets in this matchup. Plus, find our best bet for the game below:
| Bet Type | Pick | Bet Now |
|---|---|---|
| Run Line | Blue Jays +1.5 | -174 |
| Moneyline | Blue Jays | -104 |
| Total | Over 8.5 | -104 |
According to our best MLB bets, the top play to make on this game is Over 8.5 total runs.
These picks are based on our probabilities matched against the implied probabilities from the sportsbook odds.
Rays vs. Blue Jays game-day updates and essential details
Wednesday's MLB matchup between the Blue Jays and Rays at Rogers Centre is scheduled to begin at 7:07 PM ET.
- Who: Tampa Bay Rays vs. Toronto Blue Jays
- Date: Wednesday, July 22, 2026
- Time: 7:07 PM ET/4:07PM PT
- Venue: Rogers Centre
Conclusion
We predict the Blue Jays, with a 53.2% win probability, will likely beat the Rays in Wednesday's MLB matchup.
Additional tools and information for betting safely can be found in our Responsible Gambling hub.
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