St Louis City vs. San Diego FC Prediction, Odds, Picks, and MLS Season Pass Discount Code [5/10/2025]

MLS action continues on Saturday at 8:30PM ET as San Diego FC locks horns with St Louis City at Energizer Park in St. Louis, Missouri.

Based on updated simulations, Dimers' proven MLS model (see Dimers Pro for full access) predicts St Louis City as the most likely winner of today's game.

"Our team has used the latest data to run 10,000 simulations of Saturday's St Louis City-San Diego FC game," said Ryan Leaver from Dimers.

"By incorporating recent updates and various factors, our prediction gives St Louis City a 38.5% chance of winning, San Diego FC a 37.1% chance, and a 24.4% chance of a draw."

For further insights into Saturday's matchup, including best bets and picks, visit our interactive St Louis City vs. San Diego FC predictions page.

St Louis City vs. San Diego FC Prediction: Who Will Win?

Using powerful machine learning and data, we have simulated the result of Saturday's MLS matchup between St Louis City and San Diego FC 10,000 times as part of our MLS predictions coverage.

Our leading predictive model suggests a 38.5% chance of St Louis City winning, a 37.1% chance for San Diego FC, and a 24.4% chance of a draw.

Additionally, the 2.5-goal over/under has a 57% chance of going over, according to our model.

St Louis City vs. San Diego FC Odds

We have sourced the best MLS odds in America for this game, which are listed here:

Moneyline

St Louis City	San Diego FC	Draw
+190	+125	+295

Total Goals

Over 2.5	Under 2.5
-170	+135

All odds are correct at the time of publication and are subject to change.

Make the most of your sports betting experience by exploring our comprehensive list of US betting apps, and the latest sportsbooks in 2025, ensuring you never miss a top new-user deal.

St Louis City vs. San Diego FC Picks and Best Bets

Our model's strongest edge in today's St Louis City vs. San Diego FC matchup is on the moneyline.

Our expert predictions, matched against the best odds, reveal the best MLS picks and MLS best bets for every game throughout the season.

Unlimited access to our complete suite of picks, including this one, is available via Dimers Pro.

St Louis City vs. San Diego FC: Correct Score Predictions

The top three most likely final scores, according to our model, are listed below, with a 1-1 draw being the most probable:

Final Score	Probability
STL 1-1 San Diego FC	11.3%
STL 2-1 San Diego FC	8.5%
STL 1-2 San Diego FC	8.3%

These predictions are based on each team's average score after 10,000 simulations, which means the most likely correct score may differ from our predicted winner.

St Louis City vs. San Diego FC Game-Day Updates and Essential Details

Saturday's matchup between St Louis City and San Diego FC in MLS at Energizer Park is scheduled to begin at 8:30PM ET.

• Who: St Louis City vs. San Diego FC
• Date: Saturday, May 10, 2025
• Time: 8:30PM ET/5:30PM PT
• Venue: Energizer Park (St. Louis, Missouri)

Dimers.com's full preview of Saturday's St Louis City vs. San Diego FC matchup includes our prediction, picks and the latest betting odds.

Before making any San Diego FC vs. St Louis City picks, be sure to check out the latest MLS predictions and betting advice from Dimers Pro.

Conclusion

According to our computer model, St Louis City has a 38.5% win probability on Saturday, San Diego FC has a 37.1% win probability, and there is a 24.4% chance that the game will end in a draw.

AI and automation have enhanced this article to quickly deliver accurate St Louis City vs. San Diego FC insights, with human oversight ensuring high editorial quality. Our predictions are sourced from up-to-date data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

Note: Clicking links to our partners may earn us a referral fee. Learn about how we review products and services.

More on MLS

Keep up with the latest MLS news and parlay picks throughout the season.