Cardinals vs. Nationals Prediction: Washington Predicted to Win Friday's MLB Matchup [5/9/2025]

The Washington Nationals will take on the St. Louis Cardinals, in what is expected to be a tight MLB game, at Nationals Park on Friday, commencing at 6:45PM ET.

The Nationals will have Mitchell Parker (3-2, 3.48 ERA) as their starting pitcher, while the Cardinals have opted for Erick Fedde (2-3, 4.78 ERA).

Based on updated simulations, Dimers' proven MLB model (see Dimers Pro for full access) predicts the Nationals as the most likely winner of today's game.

"Employing the latest data, our experts simulated Friday's St. Louis-Washington game 10,000 times," said Dimers' Chief Content Officer, Nick Slade.

"After computing the latest updates and thousands of other inputs, we predict the Nationals' chance of winning is 53%, while the Cardinals' is 47%."

For further insights into Friday's matchup, including best bets and picks, visit our interactive Cardinals vs. Nationals predictions page.

Nationals vs. Cardinals Prediction: Who Will Win?

Using trusted machine learning and data, we have simulated the result of Friday's MLB game between the Cardinals and Nationals 10,000 times as part of our MLB predictions coverage.

Our leading predictive model currently gives the Nationals a 53% chance of beating the Cardinals.

According to our model, the 8.5-run over/under has a 51% chance of going over.

Cardinals vs. Nationals Odds [5/9/2025]

We have sourced the best MLB odds in America for this game, which are listed here:

Bet Type	Cardinals	Nationals
Moneyline	-110	-106
Total	o8.5 (-115)	u8.5 (+100)

All odds are correct at the time of publication and are subject to change.

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Cardinals vs. Nationals Picks and Best Bets

Our model's biggest edge in today's Cardinals vs. Nationals matchup is on the moneyline.

Our expert predictions, aligned with the latest odds, reveal the best MLB picks and MLB best bets for every game throughout the season.

Unlimited access to our complete set of picks, including this one, is available via Dimers Pro.

Calling Our Shot's Best Bets

Calling Our Shot produces daily MLB betting content, including the best bets featured below.

Cardinals vs. Nationals Game-Day Updates and Essential Details

Friday's MLB game between the Nationals and Cardinals at Nationals Park is scheduled to start at 6:45PM ET.

• Who: St. Louis Cardinals vs. Washington Nationals
• Date: Friday, May 9, 2025
• Time: 6:45PM ET/3:45PM PT
• Venue: Nationals Park

Dimers.com's in-depth preview of Friday's Cardinals vs. Nationals matchup includes our prediction, picks and the latest betting odds.

Before making any St. Louis vs. Washington picks, be sure to check out the latest MLB predictions and betting advice from Dimers Pro.

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Conclusion

We predict the Nationals, with a 53% win probability, will likely beat the Cardinals on Friday.

AI and automation have enhanced this article to quickly deliver accurate Cardinals vs. Nationals insights, with human oversight ensuring high editorial quality. Our predictions are sourced from the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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