Blues vs. Islanders prediction: Islanders favored to win Saturday's NHL matchup [11/22/2025]

The NY Islanders and St. Louis Blues will meet in the NHL at UBS Arena on Saturday, starting at 3:30PM ET.

Based on updated simulations, Dimers' proven NHL model gives the Islanders a slight edge with a 53% win probability over the Blues.

This article offers a closer look at Saturday's Blues vs. Islanders matchup, including projected goal scorers, best bets and player prop picks.

Blues vs. Isles prediction: Who will win and cover?

As part of Dimers' NHL predictions coverage—and following a review of recent results—our pregame model has generated moneyline, puck line, and over/under probabilities for Saturday's clash between the Blues and Islanders.

Our leading predictive model gives the Islanders a 53% chance of defeating the Blues.

According to our model, the Blues (+1.5) have a 68% chance of covering the puck line, while the over/under total of six goals has an equal 50-50 chance of hitting.

Blues vs. Islanders odds

We have researched the best NHL odds in America for this game, which are listed here:

Bet Type	Blues	Islanders
Puck Line	+1.5 (-210)	-1.5 (+185)
Moneyline	+118	-135
Total	o6 (-105)	u6 (-115)

All odds are correct at the time of publication and are subject to change.

Blues vs. Islanders picks and best bet

After matching our predictions against the best current odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:

Bet Type	Pick	Bet Now
Puck Line	Blues +1.5	-210
Moneyline	Blues	+118
Total	Over 6	-105

According to our NHL best bets, the top play to make on this game is Blues to win.

Blues vs. Islanders player props

Who will score a goal in Blues vs. Islanders?

According to our model, Bo Horvat is most likely to score an anytime goal in Blues vs. Islanders.

Our projections give Horvat a 32.8% chance of scoring a goal at UBS Arena, while the star is a 6.7% chance of netting the first goal the game.

Anytime goal scorer predictions

St. Louis Blues

Player	Anytime Goal Probability
Jordan Kyrou	30.6%
Dylan Holloway	27.1%
Jake Neighbours	25.9%
Dalibor Dvorsky	23.8%
Robert Thomas	22.2%

NY Islanders

Player	Anytime Goal Probability
Bo Horvat	32.8%
Max Shabanov	25.5%
Kyle Palmieri	24.7%
Mathew Barzal	23.8%
Simon Holmstrom	23.5%

First goal scorer predictions

St. Louis Blues

Player	First Goal Probability
Jordan Kyrou	5.9%
Dylan Holloway	5.0%
Jake Neighbours	4.9%
Dalibor Dvorsky	4.6%
Robert Thomas	4.0%

NY Islanders

Player	First Goal Probability
Bo Horvat	6.7%
Kyle Palmieri	4.4%
Simon Holmstrom	4.4%
Max Shabanov	4.3%
Mathew Barzal	4.2%

Blues vs. Isles game-day updates and essential details

Saturday's game between the Islanders and Blues at UBS Arena is scheduled to begin at 3:30PM ET.

• Who: St. Louis Blues vs. NY Islanders
• Date: Saturday, November 22, 2025
• Time: 3:30PM ET/12:30PM PT
• Venue: UBS Arena

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Conclusion

We predict the Islanders, with a 53% win probability, will likely beat the Blues on Saturday.

AI and automation have enhanced this article to quickly deliver accurate Blues vs. Islanders insights, with human oversight ensuring high editorial quality. Our predictions are based on the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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