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Blues vs. Panthers prediction: Florida favored to win Saturday's NHL matchup [12/20/2025]

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Written by Nick Slade

Get St. Louis Blues vs Florida Panthers predictions for NHL Saturday.

St. Louis Blues-Florida Panthers Predictions and Game Preview.
St. Louis Blues vs. Florida Panthers NHL prediction for Saturday, December 20, 2025.

The Florida Panthers will face the St. Louis Blues in NHL action at Amerant Bank Arena on Saturday, beginning at 6:00 PM ET.

Based on updated simulations, Dimers' advanced NHL model predicts the Panthers as the most likely winner of the Blues vs. Panthers game.

This article offers further insights into Saturday's matchup, including projected goal scorers, best bets and player prop picks.

Blues vs. Panthers prediction: Who will win and cover?

Using powerful machine learning and data, we have simulated the outcome of Saturday's NHL matchup between the Blues and Panthers 10,000 times as part of our NHL predictions coverage.

Our famous predictive model currently gives the Panthers a 62% chance of defeating the Blues.

According to our model, the Blues (+1.5) have a 61% chance of covering the puck line, while the over/under total of 5.5 goals has a 53% chance of going over.

 

Blues vs. Panthers odds

We have researched the best NHL odds in America for this game, which are listed here:

Bet Type Blues Panthers
Puck Line +1.5 (-160) -1.5 (+142)
Moneyline +150 -180
Total o5.5 (-114) u5.5 (-102)

All odds are correct at the time of publication and are subject to change.

Blues vs. Panthers picks and best bet

After matching our predictions against the best current odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:

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Written by
Nick Slade
Chief Content Officer

Nick Slade, with nearly two decades of experience, is the Chief Content Officer at Cipher Sports Technology Group, overseeing content for Dimers. He specializes in soccer, NBA, and NHL betting, leveraging predictive analytics and machine learning to provide accurate betting insights.

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