Blues vs. Panthers prediction: Florida favored to win Saturday's NHL matchup [12/20/2025]

The Florida Panthers will face the St. Louis Blues in NHL action at Amerant Bank Arena on Saturday, starting at 6:00 PM ET.

Based on the latest simulation results, Dimers' advanced NHL model predicts the Panthers as the most likely winner of the Blues vs. Panthers game.

This article offers a closer look at Saturday's matchup, including projected goal scorers, best bets and player prop picks.

Blues vs. Panthers prediction: Who will win and cover?

Using powerful machine learning and statistical analysis, we have simulated the outcome of Saturday's NHL game between the Blues and Panthers 10,000 times as part of our NHL predictions coverage.

Our famous predictive model currently gives the Panthers a 61% chance of defeating the Blues.

According to our model, the Blues (+1.5) have a 61% chance of covering the puck line, while the over/under total of 5.5 goals has a 54% chance of going over.

Blues vs. Panthers odds

We have researched the best NHL odds in America for this game, which are listed here:

Bet Type	Blues	Panthers
Puck Line	+1.5 (-170)	-1.5 (+150)
Moneyline	+146	-175
Total	o5.5 (-110)	u5.5 (-105)

All odds are correct at the time of publication and are subject to change.

Blues vs. Panthers picks and best bet

After matching our predictions against the best current odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:

Bet Type	Pick	Bet Now
Puck Line	Panthers -1.5	+150
Moneyline	Blues	+146
Total	Over 5.5	-110

According to our best NHL bets, the top play to make on this game is Over 5.5 total goals.

Blues vs. Panthers player props

Who will score a goal in Blues vs. Panthers?

According to our model, Sam Reinhart is most likely to score an anytime goal in Blues vs. Panthers.

Our projections give Reinhart a 42.7% chance of scoring a goal at Amerant Bank Arena, while the star is a 9.1% chance of netting the first goal the game.

Anytime goal scorer predictions

St. Louis Blues

Player	Anytime Goal Probability
Robert Thomas	26.1%
Jake Neighbours	25.8%
Jonatan Berggren	24.2%
Pavel Buchnevich	21.9%
Pius Suter	21.6%

Florida Panthers

Player	Anytime Goal Probability
Sam Reinhart	42.7%
Brad Marchand	38.4%
Sam Bennett	36.0%
Carter Verhaeghe	30.1%
Anton Lundell	24.1%

First goal scorer predictions

St. Louis Blues

Player	First Goal Probability
Robert Thomas	4.7%
Jonatan Berggren	4.7%
Jake Neighbours	4.5%
Pavel Buchnevich	3.9%
Dalibor Dvorsky	3.7%

Florida Panthers

Player	First Goal Probability
Sam Reinhart	9.1%
Brad Marchand	8.4%
Sam Bennett	7.6%
Carter Verhaeghe	6.0%
Anton Lundell	4.6%

Blues vs. Panthers game-day updates and essential details

Saturday's action between the Panthers and Blues at Amerant Bank Arena is scheduled to start at 6:00 PM ET.

• Who: St. Louis Blues vs. Florida Panthers
• Date: Saturday, December 20, 2025
• Time: 6:00 PM ET/3:00PM PT
• Venue: Amerant Bank Arena

Conclusion

We predict the Panthers, with a 61% win probability, will likely beat the Blues on Saturday.

AI and automation have enhanced this article to quickly deliver accurate Blues vs. Panthers insights, with human oversight ensuring high editorial quality. Our predictions are based on up-to-date data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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