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St. John's vs. DePaul prediction: St. John's favored to win women's college basketball matchup [2/10/2026]

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Written by Ryan Leaver

Get St. John's vs DePaul predictions for college basketball Tuesday.

St. John's-DePaul Predictions and Game Preview.
St. John's vs. DePaul women's college basketball prediction for Tuesday, February 10, 2026.

DePaul will face the favored St. John's in women's college basketball action at Wintrust Arena on Tuesday, starting at 7:00 PM ET.

Based on updated simulations, Dimers' new women's basketball model projects St. John's as the most likely winner of the St. John's vs. DePaul game.

This article offers a closer look at Tuesday's matchup, including best bets and picks.

St. John's vs. DePaul prediction: Who will win?

Using innovative machine learning and statistical analysis, we have simulated the result of Tuesday's women's basketball matchup between St. John's and DePaul 10,000 times as part of our women's college basketball predictions coverage.

Our famous predictive model gives St. John's a 77% chance of defeating DePaul.

According to our model, the over/under total of 127.5 points has a 51% chance of going over.

 

St. John's vs. DePaul odds

We have researched the best women's college basketball odds in America for this game, which are listed here:

Bet Type St. John's DePaul
Spread -7.5 (-106) +7.5 (-125)
Moneyline -380 +250
Total o127.5 (-114) u127.5 (-114)

All odds are correct at the time of publication and are subject to change.

St. John's vs. DePaul picks and best bet

After matching our predictions against the best available odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:

Bet Type Pick Bet Now
Spread DePaul +7.5 -125
Moneyline St. John's -380
Total Over 127.5 -114

According to our best women's college basketball bets, the top play to make on this game is Over 127.5 total points.

 

St. John's vs. DePaul game-day updates and essential details

Tuesday's women's basketball game between DePaul and St. John's at Wintrust Arena is scheduled to start at 7:00 PM ET.

  • Who: St. John's vs. DePaul
  • Date: Tuesday, February 10, 2026
  • Time: 7:00 PM ET/4:00PM PT
  • Venue: Wintrust Arena

Conclusion

We predict St. John's, with a 77% win probability, will likely beat DePaul on Tuesday.

AI and automation have enhanced this article to quickly deliver accurate St. John's vs. DePaul insights, with human oversight ensuring high editorial quality. Our predictions are based on up-to-date data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

Note: Clicking links to our partners may earn us a referral fee. Learn about how we review products and services.

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Written by
Ryan Leaver
Senior Sports and Betting Editor

Ryan Leaver uses advanced statistical models and simulations to predict outcomes and provide predictions for the NBA, NFL, college football, college basketball, and soccer. He offers detailed game previews, best bets, props, and futures articles.

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