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Southern Indiana vs. Tennessee prediction: Why Tennessee is favored to win women's college basketball matchup [12/22/2025]

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Written by Ryan Leaver

Get Southern Indiana vs Tennessee predictions for college basketball Monday.

Southern Indiana-Tennessee Predictions and Game Preview.
Southern Indiana vs. Tennessee women's college basketball prediction for Monday, December 22, 2025.

Women's college basketball action continues on Monday at 6:30 PM ET as Southern Indiana squares off with Tennessee at Thompson-Boling Arena.

Based on the latest simulations, Dimers' new women's basketball model predicts Tennessee as the most likely winner of the Southern Indiana vs. Tennessee game.

This article offers a closer look at Monday's matchup, including best bets and picks.

Southern Indiana vs. Tennessee prediction: Who will win?

Using powerful machine learning and data, we have simulated the outcome of Monday's women's basketball game between Southern Indiana and Tennessee 10,000 times as part of our women's college basketball predictions coverage.

Our independent predictive model currently gives Tennessee a 99% chance of beating Southern Indiana.

According to our model, the 143.5-point over/under has a 56% chance of going over.

 

Southern Indiana vs. Tennessee odds

We have sourced the best women's college basketball odds in America for this game, which are listed here:

Bet Type Southern Indiana Tennessee
Spread +35.5 (-114) -35.5 (-114)
Total o143.5 (-114) u143.5 (-114)

All odds are correct at the time of publication and are subject to change.

Southern Indiana vs. Tennessee picks and best bet

After matching our predictions against the best current odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:

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Written by
Ryan Leaver
Senior Sports and Betting Editor

Ryan Leaver uses advanced statistical models and simulations to predict outcomes and provide predictions for the NBA, NFL, college football, college basketball, and soccer. He offers detailed game previews, best bets, props, and futures articles.

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