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Southern Indiana vs. Tennessee prediction: Why Tennessee is favored to win women's college basketball matchup [12/22/2025]
Get Southern Indiana vs Tennessee predictions for college basketball Monday.

Women's college basketball action continues on Monday at 6:30 PM ET as Southern Indiana squares off with Tennessee at Thompson-Boling Arena.
Based on the latest simulations, Dimers' new women's basketball model predicts Tennessee as the most likely winner of the Southern Indiana vs. Tennessee game.
This article offers a closer look at Monday's matchup, including best bets and picks.
Southern Indiana vs. Tennessee prediction: Who will win?
Using powerful machine learning and data, we have simulated the outcome of Monday's women's basketball game between Southern Indiana and Tennessee 10,000 times as part of our women's college basketball predictions coverage.
Our independent predictive model currently gives Tennessee a 99% chance of beating Southern Indiana.
According to our model, the 143.5-point over/under has a 56% chance of going over.
Southern Indiana vs. Tennessee odds
We have sourced the best women's college basketball odds in America for this game, which are listed here:
| Bet Type | Southern Indiana | Tennessee |
|---|---|---|
| Spread | +35.5 (-114) | -35.5 (-114) |
| Total | o143.5 (-114) | u143.5 (-114) |
All odds are correct at the time of publication and are subject to change.
Southern Indiana vs. Tennessee picks and best bet
After matching our predictions against the best current odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:
| Bet Type | Pick | Bet Now |
|---|---|---|
| Spread | Southern Indiana +35.5 | -114 |
| Total | Over 143.5 | -114 |
According to our women's college basketball best bets, the top play to make on this game is over 143.5 points.
Southern Indiana vs. Tennessee game-day updates and essential details
Monday's women's basketball action between Tennessee and Southern Indiana at Thompson-Boling Arena is scheduled to commence at 6:30 PM ET.
- Who: Southern Indiana vs. Tennessee
- Date: Monday, December 22, 2025
- Time: 6:30 PM ET/3:30PM PT
- Venue: Thompson-Boling Arena
Conclusion
We predict Tennessee, with a 99% win probability, will likely beat Southern Indiana on Monday.
AI and automation have enhanced this article to quickly deliver accurate Southern Indiana vs. Tennessee insights, with human oversight ensuring high editorial quality. Our predictions are sourced from the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.
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