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Southern Indiana vs. Tennessee prediction: Why Tennessee is favored to win women's college basketball matchup [12/22/2025]
Updated: | First published:
Written by Ryan Leaver, Senior Sports and Betting Editor
Get Southern Indiana vs Tennessee predictions for college basketball Monday.
Tennessee and Southern Indiana will meet in the women's college basketball at Thompson-Boling Arena on Monday, starting at 6:30 PM ET.
Based on updated simulations, Dimers' new women's basketball model predicts Tennessee as the most likely winner of the Southern Indiana vs. Tennessee game.
This article offers further insights into Monday's matchup, including best bets and picks.
Southern Indiana vs. Tennessee prediction: Who will win?
Using innovative machine learning and statistical analysis, we have simulated the result of Monday's women's basketball matchup between Southern Indiana and Tennessee 10,000 times as part of our women's college basketball predictions coverage.
Our independent predictive model currently gives Tennessee a 99% chance of defeating Southern Indiana.
According to our model, the over/under total of 143.5 points has a 56% chance of going over.
Southern Indiana vs. Tennessee odds
We have sourced the best women's college basketball odds in America for this game, which are listed here:
| Bet Type | Southern Indiana | Tennessee |
|---|---|---|
| Spread | +35.5 (-105) | -35.5 (-114) |
| Total | o143.5 (-105) | u143.5 (-114) |
All odds are correct at the time of publication and are subject to change.
Southern Indiana vs. Tennessee picks and best bet
After matching our probabilities against the best available odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:
| Bet Type | Pick | Bet Now |
|---|---|---|
| Spread | Southern Indiana +35.5 | -105 |
| Total | Over 143.5 | -105 |
According to our women's college basketball best bets, the top play to make on this game is over 143.5 points.
Southern Indiana vs. Tennessee game-day updates and essential details
Monday's women's basketball matchup between Tennessee and Southern Indiana at Thompson-Boling Arena is scheduled to begin at 6:30 PM ET.
- Who: Southern Indiana vs. Tennessee
- Date: Monday, December 22, 2025
- Time: 6:30 PM ET/3:30PM PT
- Venue: Thompson-Boling Arena
Conclusion
We predict Tennessee, with a 99% win probability, will likely beat Southern Indiana on Monday.
AI and automation have enhanced this article to quickly deliver accurate Southern Indiana vs. Tennessee insights, with human oversight ensuring high editorial quality. Our predictions are sourced from up-to-date data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.
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Ryan Leaver uses advanced statistical models and simulations to predict outcomes and provide predictions for the NBA, NFL, college football, college basketball, and soccer. He offers detailed game previews, best bets, props, and futures articles.
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