Mariners vs. Twins prediction: Why Seattle is favored to win Wednesday's MLB matchup [4/29/2026]
Get Seattle Mariners vs Minnesota Twins predictions for MLB Wednesday.

The Minnesota Twins will face the Seattle Mariners in MLB action at Target Field on Wednesday, beginning at 1:40 PM ET.
The Twins will have Taj Bradley (3-1, 2.91 ERA) as their starting pitcher, pitting him against George Kirby (4-2, 2.98 ERA) for the Mariners.
Based on the latest simulation results, Dimers' advanced MLB model predicts the Mariners as the most likely winner of the Mariners vs. Twins game.
This article offers a closer look at Wednesday's matchup, including best bets and picks.
Mariners vs. Twins prediction: Who will win and cover?
Our famous predictive model gives the Mariners a 55% chance of defeating the Twins.
According to our model, the Twins (+1.5) have a 57% chance of covering the run line, while the 8-run over/under has a 52% chance of going over.
Mariners vs. Twins odds [4/29/2026]
We have sourced the best MLB odds in America for this game, which are listed here:
| Bet Type | Mariners | Twins |
|---|---|---|
| Run Line | -1.5 (+122) | +1.5 (-136) |
| Moneyline | -130 | +116 |
| Total | o8 (-110) | u8 (-102) |
All odds are correct at the time of publication and are subject to change.
Mariners vs. Twins picks and best bet
After matching our probabilities against the best available odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:
| Bet Type | Pick | Bet Now |
|---|---|---|
| Run Line | Twins +1.5 | -136 |
| Moneyline | Twins | +116 |
| Total | Over 8 | -110 |
According to our best MLB bets, the top play to make on this game is Over 8 total runs.
These picks are based on our probabilities matched against the implied probabilities from the sportsbook odds.
Mariners vs. Twins game-day updates and essential details
Wednesday's MLB matchup between the Twins and Mariners at Target Field is scheduled to commence at 1:40 PM ET.
- Who: Seattle Mariners vs. Minnesota Twins
- Date: Wednesday, April 29, 2026
- Time: 1:40 PM ET/10:40AM PT
- Venue: Target Field
Conclusion
We predict the Mariners, with a 55% win probability, will likely beat the Twins in Wednesday's MLB matchup.
Additional tools and information for betting safely can be found in our Responsible Gambling hub.



