San Diego vs. Seattle prediction: Seattle favored to win men's college basketball matchup [3/6/2026]

Seattle and San Diego will meet in men's college basketball action at Orleans Arena on Friday, starting at 11:30 PM ET.

Based on the latest simulation results, Dimers' proven college basketball model projects Seattle as the most likely winner of the San Diego vs. Seattle game.

This article offers further insights into Friday's matchup, including an expanded look at the predicted score, best bets and picks.

San Diego vs. Seattle prediction: Who will win and cover?

Using trusted machine learning and data analysis, we have simulated the outcome of Friday's NCAA basketball game between San Diego and Seattle 10,000 times as part of our men's college basketball predictions coverage.

Our famous predictive model gives Seattle a 79% chance of defeating San Diego. Our predicted final score has Seattle winning 74-66.

According to our model, San Diego (+8.5) has a 51% chance of covering the spread, while the over/under total of 139.5 points has a 53% chance of going over.

San Diego vs. Seattle odds

We have researched the best men's college basketball odds in America for this game, which are listed here:

Bet Type	San Diego	Seattle
Spread	+8.5 (-102)	-8.5 (-105)
Moneyline	+340	-400
Total	o139.5 (-105)	u139.5 (-105)

All odds are correct at the time of publication and are subject to change.

San Diego vs. Seattle picks and best bet

After matching our probabilities against the best available odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:

Bet Type	Pick	Bet Now
Spread	San Diego +8.5	-102
Moneyline	Seattle	-400
Total	Over 139.5	-105

According to our men's college basketball best bets, the top play to make on this game is Over 139.5 total points.

These picks are based on our probabilities matched against the implied probabilities from the sportsbook odds.

San Diego vs. Seattle game-day updates and essential details

Friday's men's college basketball game between Seattle and San Diego at Orleans Arena is scheduled to begin at 11:30 PM ET.

• Who: San Diego vs. Seattle
• Date: Friday, March 6, 2026
• Time: 11:30 PM ET/8:30PM PT
• Venue: Orleans Arena

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Conclusion

We predict Seattle, with a 79% win probability, will likely beat San Diego on Friday.

AI and automation have enhanced this article to quickly deliver accurate San Diego vs. Seattle insights, with human oversight ensuring high editorial quality. Our predictions are drawn from the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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