Samford vs. Southern University prediction: Southern University favored to win women's March Madness First Four matchup [3/19/2026]

Southern University will square off with Samford, in what is expected to be a close women's college basketball game, at Colonial Life Arena on Thursday, commencing at 7:00 PM ET.

Based on updated simulation results, Dimers' new women's basketball model gives Southern University a slight edge with a 52% win probability over Samford.

This article offers an expanded analysis of Thursday's Samford vs. Southern University matchup, including best bets and picks.

Samford vs. Southern University prediction: Who will win and advance to the First Round?

Using innovative machine learning and statistical analysis, we have simulated the outcome of Thursday's NCAAW Tournament matchup between Samford and Southern University 10,000 times as part of our women's college basketball predictions coverage.

Our famous predictive model gives Southern University a 52% chance of beating Samford.

According to our model, the 117.5-point over/under has a 51% chance of staying under.

Samford vs. Southern University odds

We have sourced the best women's college basketball odds in America for this game, which are listed here:

All odds are correct at the time of publication and are subject to change.

Samford vs. Southern University picks and best bet

After matching our probabilities against the best current odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:

According to our best women's college basketball bets, the top play to make on this game is Samford to win.

These picks are based on our probabilities matched against the implied probabilities from the sportsbook odds.

Samford vs. Southern University game-day updates and essential details

Thursday's women's basketball matchup between Southern University and Samford at Colonial Life Arena is scheduled to begin at 7:00 PM ET.

• Who: Samford vs. Southern University
• Date: Thursday, March 19, 2026
• Time: 7:00 PM ET/4:00PM PT
• Venue: Colonial Life Arena
• March Madness stage: First Four

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Conclusion

We predict Southern University, with a 52% win probability, will likely beat Samford this women's March Madness First Four matchup.

AI and automation have enhanced this article to quickly deliver accurate Samford vs. Southern University insights, with human oversight ensuring high editorial quality. Our predictions are sourced from the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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