Real Madrid vs. Sevilla prediction, odds, La Liga picks [12/20/2025]

Real Madrid and Sevilla are scheduled to meet in La Liga on Saturday, starting at 3:00 PM ET.

Based on updated simulation results, Dimers' proven La Liga model projects Real Madrid as the most likely winner of the Real Madrid vs. Sevilla game.

This article offers an expanded analysis of Saturday's matchup, including best bets and picks.

Real Madrid vs. Sevilla prediction: Who will win?

Using innovative machine learning and data, we have simulated the result of Saturday's La Liga match between Real Madrid and Sevilla 10,000 times as part of our La Liga predictions coverage.

Our famous predictive model indicates a 73.0% chance of Real Madrid winning, an 11.1% chance for Sevilla, and a 15.9% chance of a draw.

Real Madrid vs. Sevilla odds

We have researched the best La Liga odds in America for this game, which are listed here:

All odds are correct at the time of publication and are subject to change.

Real Madrid vs. Sevilla picks and best bet

After matching our predictions against the best current odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:

According to our La Liga best bets, the top play to make on this game is Sevilla to win.

Real Madrid vs. Sevilla: Correct score and BTTS predictions

Here are the top three most likely final scoresaccording to our model, with a 2-0 Real Madrid win being the most probable:

When it comes to the both teams to score (BTTS) market, we project a 54.6% chance of the yes hitting, and a 45.4% probability of at least one team keeping a clean sheet.

These predictions are based on each team's average score after 10,000 simulations.

Real Madrid vs. Sevilla game-day updates and essential details

Saturday's La Liga matchup between Real Madrid and Sevilla is scheduled to start in the USA at 3:00 PM ET.

• Who: Real Madrid vs. Sevilla
• Date: Saturday, December 20, 2025
• Time: 3:00 PM ET/12:00PM PT

Conclusion

According to our computer model, Real Madrid has a 73.0% win probability on Saturday, Sevilla has an 11.1% win probability, and there is a 15.9% chance that the game will end in a draw.

AI and automation have enhanced this article to quickly deliver accurate Real Madrid vs. Sevilla insights, with human oversight ensuring high editorial quality. Our predictions are sourced from the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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