Real Madrid vs. Barcelona prediction, odds, La Liga picks [10/26/2025]

Real Madrid will square off with Barcelona in La Liga action on Sunday, commencing at 11:15AM ET.

Based on the latest simulations, Dimers' advanced La Liga model predicts Real Madrid as the most likely winner of the Real Madrid vs. Barcelona game.

This article offers an expanded analysis of Sunday's matchup, including best bets and picks.

Real Madrid vs. Barcelona prediction: Who will win?

Using innovative machine learning and data analysis, we have simulated the result of Sunday's La Liga match between Real Madrid and Barcelona 10,000 times as part of our La Liga predictions coverage.

Our leading predictive model currently suggests a 48.9% chance of Real Madrid winning, a 29.8% chance for Barcelona, and a 21.3% chance of a draw.

Real Madrid vs. Barcelona odds

We have sourced the best La Liga odds in America for this game, which are listed here:

All odds are correct at the time of publication and are subject to change.

Real Madrid vs. Barcelona picks and best bet

Our predictions, matched with the available odds, reveal the top betting picks for this game, detailed in Dimers' La Liga best bets, crafted from expert modeling and analysis:

Real Madrid vs. Barcelona: Correct score and BTTS predictions

The top three most likely final scores, according to our model, are listed below, with a 2-1 Real Madrid win being the most probable:

When it comes to the both teams to score (BTTS) market, we project a 69.2% chance of the yes hitting, and a 30.8% probability of at least one team keeping a clean sheet.

These predictions are based on each team's average score after 10,000 simulations.

Real Madrid vs. Barcelona game-day updates and essential details

Sunday's La Liga matchup between Real Madrid and Barcelona is scheduled to commence in the United States at 11:15AM ET.

• Who: Real Madrid vs. Barcelona
• Date: Sunday, October 26, 2025
• Time: 11:15AM ET/8:15AM PT

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Conclusion

According to our computer model, Real Madrid has a 48.9% win probability on Sunday, Barcelona has a 29.8% win probability, and there is a 21.3% chance that the game will end in a draw.

AI and automation have enhanced this article to quickly deliver accurate Real Madrid vs. Barcelona insights, with human oversight ensuring high editorial quality. Our predictions are drawn from up-to-date data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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More on La Liga

Stay informed with the latest La Liga news and parlay picks throughout the season. Plus, our La Liga futures odds offer the most accurate projections for each La Liga title contender.

Make the most of your sports betting experience by exploring our comprehensive list of US betting apps, and the latest sportsbooks in 2025, ensuring you never miss a top new-user deal.