Prairie View A&M vs. Lehigh prediction: Lehigh favored to win men's March Madness First Four matchup [3/18/2026]

Lehigh and Prairie View A&M will lock horns in March Madness First Four action at UD Arena on Wednesday, with tipoff at 6:40 PM ET.

Based on the latest simulation results, Dimers' proven college basketball model projects Lehigh as the most likely winner of the Prairie View A&M vs. Lehigh game.

This article offers a closer look at Wednesday's matchup, including an expanded look at the predicted score, best bets and picks.

Prairie View A&M vs. Lehigh prediction: Who will win and advance to the First Round?

Using powerful machine learning and data analysis, we have simulated the result of Wednesday's NCAAM Tournament game between Prairie View A&M and Lehigh 10,000 times as part of our men's college basketball predictions coverage.

Our famous predictive model currently gives Lehigh a 59% chance of defeating Prairie View A&M. Our predicted final score has Lehigh winning 73-70.

According to our model, the bookmakers have got it right, and Prairie View A&M and Lehigh each have a 50% chance of covering the spread, while the over/under total of 141.5 points has a 53% chance of going over.

Prairie View A&M vs. Lehigh odds

We have sourced the best men's college basketball odds in America for this game, which are listed here:

All odds are correct at the time of publication and are subject to change.

Prairie View A&M vs. Lehigh picks and best bet

After matching our predictions against the best current odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below: