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Trail Blazers vs. Thunder prediction: Oklahoma City favored to win Wednesday's NBA matchup [12/31/2025]

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Written by Dave Garofolo

Get Portland Trail Blazers vs Oklahoma City Thunder predictions for NBA Wednesday.

Portland Trail Blazers-Oklahoma City Thunder Predictions and Game Preview.
Portland Trail Blazers vs. Oklahoma City Thunder NBA prediction for Wednesday, December 31, 2025.

The Oklahoma City Thunder will face the Portland Trail Blazers in NBA action at Paycom Center on Wednesday, starting at 8:00 PM ET.

Based on the latest simulations and today’s injury updates, Dimers' advanced NBA model predicts the Thunder as the most likely winner of the Trail Blazers vs. Thunder game.

This prediction follows the latest NBA Injury Report, which suggests the Thunder lineup will feature stars like Shai Gilgeous-Alexander, Jalen Williams and Chet Holmgren, while the Trail Blazers will be led by Deni Avdija, Shaedon Sharpe and Toumani Camara.

This article offers a closer look at Wednesday's matchup, including an expanded look at the predicted score, best bets and player prop picks.

Blazers vs. Thunder prediction: Who will win and cover?

Using innovative machine learning and data, we have simulated the result of Wednesday's NBA matchup between the Trail Blazers and Thunder 10,000 times as part of our NBA predictions coverage.

Our independent predictive model gives the Thunder an 87% chance of defeating the Trail Blazers. Our predicted final score has the Thunder winning 122-109.

According to our model, the Trail Blazers (+15.5) have a 58% chance of covering the spread, while the over/under total of 232.5 points has a 51% chance of staying under.

 

Trail Blazers vs. Thunder odds

We have researched the best NBA odds in America for this game, which are listed here:

Bet Type Trail Blazers Thunder
Spread +15.5 (-105) -15.5 (-112)
Moneyline +810 -1100
Total o232.5 (-110) u232.5 (-108)

All odds are correct at the time of publication and are subject to change.

Trail Blazers vs. Thunder picks and best bet

After matching our predictions against the best current odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:

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Written by
Dave Garofolo
Content Producer

Dave Garofolo uses sophisticated AI-driven analytics to make predictions and evaluate player performances in the NBA, MLB, NFL, NHL, NCAAM, and PGA TOUR tournaments, crafting insightful game and prop previews.

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