Trail Blazers vs. Thunder prediction: Oklahoma City favored to win Wednesday's NBA matchup [12/31/2025]

NBA action continues on Wednesday at 8:00 PM ET as the Portland Trail Blazers face off with the favored Oklahoma City Thunder at Paycom Center.

Based on the latest simulation results and today’s injury reports, Dimers' proven NBA model projects the Thunder as the most likely winner of the Trail Blazers vs. Thunder game.

This prediction follows the latest NBA Injury Report, which suggests the Thunder lineup will feature stars like Shai Gilgeous-Alexander, Jalen Williams and Chet Holmgren, while the Trail Blazers will rely on Deni Avdija, Shaedon Sharpe and Toumani Camara.

This article offers an expanded analysis of Wednesday's matchup, including an expanded look at the predicted score, best bets and player prop picks.

Blazers vs. Thunder prediction: Who will win and cover?

Using trusted machine learning and data, we have simulated the outcome of Wednesday's NBA game between the Trail Blazers and Thunder 10,000 times as part of our NBA predictions coverage.

Our leading predictive model currently gives the Thunder an 88% chance of defeating the Trail Blazers. Our predicted final score has the Thunder winning 122-109.

According to our model, the Trail Blazers (+15.5) have a 58% chance of covering the spread, while the over/under total of 232.5 points has a 51% chance of staying under.

Trail Blazers vs. Thunder odds

We have researched the best NBA odds in America for this game, which are listed here:

Bet Type	Trail Blazers	Thunder
Spread	+15.5 (-105)	-15.5 (-112)
Moneyline	+675	-1000
Total	o232.5 (-108)	u232.5 (-110)

All odds are correct at the time of publication and are subject to change.

Trail Blazers vs. Thunder picks and best bet

After matching our predictions against the best current odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:

Bet Type	Pick	Bet Now
Spread	Trail Blazers +15.5	-105
Moneyline	Trail Blazers	+675
Total	Under 232.5	-110

According to our best NBA bets for Wednesday, the top play to make on this game is Trail Blazers +15.5 at the spread.

Trail Blazers vs. Thunder player props

NBA prop bets are a common way to wager on Wednesday's Portland vs. Oklahoma City matchup without necessarily betting on the outcome. We use the best information available to project how each team's leading players will perform at Paycom Center.

Deni Avdija is expected to lead the Trail Blazers with 25 points, 9 rebounds and 6 assists, while Shai Gilgeous-Alexander is projected to have 31 points, 5 rebounds and 7 assists for the Thunder.

Check out our NBA player projections for a full range of projected box scores, including points, assists, rebounds and today's NBA first basket picks.

Trail Blazers prediction

Our model's projected player stats for the Trail Blazers are:

Player	PTS	REB	AST	3PM	DFS
Deni Avdija	25	9	6	3	51
Shaedon Sharpe	21	5	3	2	37
Toumani Camara	13	5	3	3	29
Caleb Love	11	3	2	2	21
Donovan Clingan	10	10	2	1	31

Thunder prediction

Projected points, rebounds, assists and three-pointers made for the Thunder:

Player	PTS	REB	AST	3PM	DFS
S. Gilgeous-Alexander	31	5	7	2	55
Jalen Williams	20	5	6	1	41
Chet Holmgren	18	8	1	1	36
Ajay Mitchell	12	3	3	1	25
Cason Wallace	8	3	3	1	23

Blazers vs. Thunder game-day updates and essential details

Wednesday's game between the Thunder and Trail Blazers at Paycom Center is scheduled to start at 8:00 PM ET.

• Who: Portland Trail Blazers vs. Oklahoma City Thunder
• Date: Wednesday, December 31, 2025
• Time: 8:00 PM ET/5:00PM PT
• Venue: Paycom Center

Conclusion

We predict the Thunder, with an 88% win probability, will likely beat the Trail Blazers on Wednesday, with Shai Gilgeous-Alexander projected for a game-high 55 fantasy points.

AI and automation have enhanced this article to quickly deliver accurate Trail Blazers vs. Thunder insights, with human oversight ensuring high editorial quality. Our predictions are based on the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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