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Eagles vs. Chargers prediction: Philadelphia favored to win ‘MNF’ Week 14, 2025

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Written by Ryan Leaver

Get Philadelphia Eagles vs Los Angeles Chargers predictions for NFL Monday.

Philadelphia Eagles-Los Angeles Chargers Predictions and Game Preview.
Philadelphia Eagles vs. Los Angeles Chargers NFL prediction for Monday, December 8, 2025.

The Los Angeles Chargers will take on the Philadelphia Eagles in NFL Week 14 action at SoFi Stadium on Monday, commencing at 8:15PM ET.

Based on updated simulation results, Dimers' advanced NFL model predicts the Eagles as the most likely winner of the Eagles vs. Chargers game.

This article offers a closer look at Monday's matchup, including projected touchdown scorers, best bets and player prop picks.

Eagles vs. Chargers prediction: Who will win ‘Monday Night Football’?

Since our Eagles-Chargers predictions earlier in the week, we have simulated the result of Monday's NFL game between the Eagles and Chargers 10,000 times as part of our NFL predictions coverage.

Our famous predictive model gives the Eagles a 58% chance of defeating the Chargers in Week 14 of the NFL season. Our predicted final score has the Eagles winning 21-20.

According to our model, the Chargers (+2.5) have a 58% chance of covering the spread, while the over/under total of 41.5 points has a 54% chance of going over.

 

To see win probabilities for every matchup this week, check out our expert NFL Week 14 straight up picks.

Eagles vs. Chargers odds

We have sourced the best NFL odds in America for this game, which are listed here:

Bet Type Eagles Chargers
Spread -2.5 (-105) +2.5 (-115)
Moneyline -130 +116
Total o41.5 (-112) u41.5 (-105)

All odds are correct at the time of publication and are subject to change.

Eagles vs. Chargers picks and best bet

After matching our predictions against the best available odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:

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Written by
Ryan Leaver
Senior Sports and Betting Editor

Ryan Leaver uses advanced statistical models and simulations to predict outcomes and provide predictions for the NBA, NFL, college football, college basketball, and soccer. He offers detailed game previews, best bets, props, and futures articles.

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