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North QLD Cowboys vs. Penrith Panthers Prediction: Panthers Predicted to Win Saturday's NRL Round 10 Matchup [5/10/2025]
Updated: | First published:
Written by Jason Bevilacqua, Head of Content and Communities
Our expert prediction for Saturday's North QLD Cowboys vs Penrith Panthers matchup.
The North QLD Cowboys and Penrith Panthers are scheduled to meet in the National Rugby League (NRL) at Queensland Country Bank Stadium on Saturday, starting at 5:35AM ET.
Based on updated simulation results, Dimers' proven NRL model (see Dimers Pro for full access) predicts the Panthers as the most likely winner of today's game.
"Our team has used the latest data to run 10,000 simulations of Saturday's Panthers-Cowboys game," said Pat Sharyon from Dimers.
"By incorporating recent updates and various other inputs, we estimate that the Panthers are more likely to win, while the Cowboys have a lower chance of victory."
For further insights into Saturday's matchup, including best bets and picks, visit our interactive Panthers vs. Cowboys predictions page.
Cowboys vs. Panthers Prediction: Who Will Win Round 10 Game?
Using innovative machine learning and statistical analysis, we have simulated the result of Saturday's NRL game between the Panthers and Cowboys 10,000 times as part of our NRL predictions coverage.
Our leading predictive model gives the Panthers a 61% chance of beating the Cowboys.
According to our model, the bookmakers have got it right, and the Panthers and Cowboys each have a 50% chance of covering the spread, while the 48.5- over/under has a 59% chance of staying under.
Panthers vs. Cowboys Odds
We have sourced the best NRL odds in America for this game, which are listed here:
| Bet Type | Panthers | Cowboys |
|---|---|---|
| H2H (Moneyline) | -179 | +143 |
| Line (Spread) | -4.5 (-110) | +4.5 (-115) |
| Total | o48.5 (-108) | u48.5 (-118) |
All odds are correct at the time of publication and are subject to change.
Make the most of your sports betting experience by exploring our comprehensive list of US betting apps, and the latest sportsbooks in 2025, ensuring you never miss a top new-user deal.
Cowboys vs. Panthers Game-Day Updates and Essential Details
Saturday's Australian rugby league action between the Cowboys and Panthers at Queensland Country Bank Stadium is scheduled to begin at 5:35AM ET.
- Who: Penrith Panthers vs. North QLD Cowboys
- Date: Saturday, May 10, 2025
- Time: 5:35AM ET/2:35AM PT
- Venue: Queensland Country Bank Stadium
The NRL is available to bet on in the US through all major sportsbooks, with there even being games played in Vegas each season as of 2024.
Dimers.com's in-depth preview of Saturday's Panthers vs. Cowboys matchup includes our prediction, picks and the latest betting odds.
Before making any Panthers vs. Cowboys picks, be sure to check out the latest NRL predictions and betting advice from Dimers Pro.
Conclusion
We predict the Panthers, with a 61% win probability, will likely beat the Cowboys on Saturday.
AI and automation have enhanced this article to quickly deliver accurate Panthers vs. Cowboys insights, with human oversight ensuring high editorial quality. Our predictions are drawn from the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.
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More on NRL
Keep up with the latest NRL betting news and parlay picks throughout the season.
Jason Bevilacqua, an expert in MLB, NHL, NBA, MLS, and NFL, delivers game previews, best bets, and props. Since 2020, as Head of Social and Community at Dimers, he has contributed insightful articles utilizing data-driven models and simulations.
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