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Ohio State vs. Iowa prediction: Why Iowa is favored to win men's college basketball matchup [2/25/2026]
Updated: | First published:
Written by Mac Douglass, Senior Editor
Get Ohio State vs Iowa predictions for college basketball Wednesday.
Iowa will face Ohio State in men's college basketball action at Carver-Hawkeye Arena on Wednesday, commencing at 9:00 PM ET.
Based on the latest simulation results, Dimers' proven college basketball model predicts Iowa as the most likely winner of the Ohio State vs. Iowa game.
This article offers an expanded analysis of Wednesday's matchup, including an expanded look at the predicted score, best bets and picks.
Ohio State vs. Iowa prediction: Who will win and cover?
Using powerful machine learning and statistical analysis, we have simulated the result of Wednesday's NCAA basketball matchup between Ohio State and Iowa 10,000 times as part of our men's college basketball predictions coverage.
Our famous predictive model gives Iowa a 70% chance of beating Ohio State. Our predicted final score has Iowa winning 75-69.
According to our model, the bookmakers have got it right, and Ohio State and Iowa each have a 50% chance of covering the spread, while the over/under total of 141.5 points has a 55% chance of going over.
Ohio State vs. Iowa odds
We have researched the best men's college basketball odds in America for this game, which are listed here:
| Bet Type | Ohio State | Iowa |
|---|---|---|
| Spread | +6.5 (-110) | -6.5 (-105) |
| Moneyline | +250 | -275 |
| Total | o141.5 (-105) | u141.5 (-114) |
All odds are correct at the time of publication and are subject to change.
Ohio State vs. Iowa picks and best bet
After matching our probabilities against the best current odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:
| Bet Type | Pick | Bet Now |
|---|---|---|
| Spread | Iowa -6.5 | -105 |
| Moneyline | Ohio State | +250 |
| Total | Over 141.5 | -105 |
According to our men's college basketball best bets, the top play to make on this game is Over 141.5 total points.
These picks are based on our probabilities matched against the implied probabilities from the sportsbook odds.
Ohio State vs. Iowa game-day updates and essential details
Wednesday's men's college basketball matchup between Iowa and Ohio State at Carver-Hawkeye Arena is scheduled to commence at 9:00 PM ET.
- Who: Ohio State vs. Iowa
- Date: Wednesday, February 25, 2026
- Time: 9:00 PM ET/6:00PM PT
- Venue: Carver-Hawkeye Arena
Conclusion
We predict Iowa, with a 70% win probability, will likely beat Ohio State on Wednesday.
AI and automation have enhanced this article to quickly deliver accurate Ohio State vs. Iowa insights, with human oversight ensuring high editorial quality. Our predictions are based on up-to-date data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.
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Mac Douglass specializes in NFL previews for the NFC South and NFC East, MLB best bets, Formula 1 race previews, and professional tennis insights. Combining predictive simulations and data-driven sports analysis, Mac provides in-depth content to elevate the betting experience for sports fans.
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