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Notre Dame vs. SMU prediction: Notre Dame favored to win NCAAW matchup [2/22/2026]

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Written by Ryan Leaver

Get Notre Dame vs SMU predictions for college basketball Sunday.

Notre Dame-SMU Predictions and Game Preview.
Notre Dame vs. SMU women's college basketball prediction for Sunday, February 22, 2026.

Women's college basketball action continues on Sunday at 6:00 PM ET as Notre Dame locks horns with SMU at Moody Coliseum.

Based on updated simulations, Dimers' new women's basketball model predicts Notre Dame as the most likely winner of the Notre Dame vs. SMU game.

This article offers further insights into Sunday's matchup, including best bets and picks.

Notre Dame vs. SMU prediction: Who will win?

Using trusted machine learning and statistical analysis, we have simulated the result of Sunday's women's basketball game between Notre Dame and SMU 10,000 times as part of our women's college basketball predictions coverage.

Our famous predictive model currently gives Notre Dame a 99% chance of defeating SMU.

According to our model, the over/under total of 144.5 points has a 52% chance of going over.

 

Notre Dame vs. SMU odds

We have sourced the best women's college basketball odds in America for this game, which are listed here:

Bet Type Notre Dame SMU
Spread -27.5 (-110) +27.5 (-110)
Total o144.5 (-110) u144.5 (-110)

All odds are correct at the time of publication and are subject to change.

Notre Dame vs. SMU picks and best bet

After matching our predictions against the best available odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:

Bet Type Pick Bet Now
Spread Notre Dame -27.5 -110
Total Over 144.5 -110

According to our women's college basketball best bets, the top play to make on this game is over 144.5 points.

These picks are based on our probabilities matched against the implied probabilities from the sportsbook odds.

 

Notre Dame vs. SMU game-day updates and essential details

Sunday's women's basketball action between SMU and Notre Dame at Moody Coliseum is scheduled to start at 6:00 PM ET.

  • Who: Notre Dame vs. SMU
  • Date: Sunday, February 22, 2026
  • Time: 6:00 PM ET/3:00PM PT
  • Venue: Moody Coliseum

Conclusion

We predict Notre Dame, with a 99% win probability, will likely beat SMU on Sunday.

AI and automation have enhanced this article to quickly deliver accurate Notre Dame vs. SMU insights, with human oversight ensuring high editorial quality. Our predictions are sourced from up-to-date data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

Note: Clicking links to our partners may earn us a referral fee. Learn about how we review products and services.

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Written by
Ryan Leaver
Senior Sports and Betting Editor

Ryan Leaver uses advanced statistical models and simulations to predict outcomes and provide predictions for the NBA, NFL, college football, college basketball, and soccer. He offers detailed game previews, best bets, props, and futures articles.

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