Northwestern vs. Purdue prediction: Why Purdue is favored to win men's college basketball matchup [3/12/2026]

Purdue will square off with Northwestern in men's college basketball action at United Center on Thursday, starting at 6:30 PM ET.

Based on updated simulation results, Dimers' advanced college basketball model projects Purdue as the most likely winner of the Northwestern vs. Purdue game.

This article offers an expanded analysis of Thursday's matchup, including an expanded look at the predicted score, best bets and picks.

Northwestern vs. Purdue prediction: Who will win and cover?

Using powerful machine learning and data, we have simulated the outcome of Thursday's NCAA basketball matchup between Northwestern and Purdue 10,000 times as part of our men's college basketball predictions coverage.

Our leading predictive model currently gives Purdue a 91% chance of defeating Northwestern. Our predicted final score has Purdue winning 78-64.

According to our model, Purdue (-13.5) has a 53% chance of covering the spread, while the over/under total of 139.5 points has a 56% chance of going over.

Northwestern vs. Purdue odds

We have researched the best men's college basketball odds in America for this game, which are listed here:

Bet Type	Northwestern	Purdue
Spread	+13.5 (-105)	-13.5 (-106)
Moneyline	+800	-1000
Total	o139.5 (-108)	u139.5 (-110)

All odds are correct at the time of publication and are subject to change.

Northwestern vs. Purdue picks and best bet

After matching our predictions against the best available odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:

Bet Type	Pick	Bet Now
Spread	Purdue -13.5	-106
Moneyline	Purdue	-1000
Total	Over 139.5	-108

According to our best men's college basketball bets, the top play to make on this game is Over 139.5 total points.

These picks are based on our probabilities matched against the implied probabilities from the sportsbook odds.

Northwestern vs. Purdue game-day updates and essential details

Thursday's men's college basketball game between Purdue and Northwestern at United Center is scheduled to start at 6:30 PM ET.

• Who: Northwestern vs. Purdue
• Date: Thursday, March 12, 2026
• Time: 6:30 PM ET/3:30PM PT
• Venue: United Center

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Conclusion

We predict Purdue, with a 91% win probability, will likely beat Northwestern on Thursday.

AI and automation have enhanced this article to quickly deliver accurate Northwestern vs. Purdue insights, with human oversight ensuring high editorial quality. Our predictions are based on up-to-date data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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