Northern Iowa vs. Illinois State prediction: Why Northern Iowa is favored to win men's college basketball matchup [3/6/2026]

Illinois State and Northern Iowa are scheduled to meet in men's college basketball action at Enterprise Center on Friday, starting at 9:30 PM ET.

Based on updated simulation results, Dimers' advanced college basketball model predicts Northern Iowa as the most likely winner of the Northern Iowa vs. Illinois State game.

This article offers an expanded analysis of Friday's matchup, including an expanded look at the predicted score, best bets and picks.

Northern Iowa vs. Illinois State prediction: Who will win and cover?

Using powerful machine learning and data analysis, we have simulated the result of Friday's NCAA basketball game between Northern Iowa and Illinois State 10,000 times as part of our men's college basketball predictions coverage.

Our famous predictive model currently gives Northern Iowa a 55% chance of defeating Illinois State. Our predicted final score has Northern Iowa winning 66-65.

According to our model, Illinois State (+1.5) has a 55% chance of covering the spread, while the over/under total of 130.5 points has a 54% chance of going over.

Northern Iowa vs. Illinois State odds

We have sourced the best men's college basketball odds in America for this game, which are listed here:

All odds are correct at the time of publication and are subject to change.

Northern Iowa vs. Illinois State picks and best bet

After matching our predictions against the best current odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below: