NFL player props today: Week 6's best props include Drew Sample [10/12/2025]

Updated: Oct 12, 2025, 3:58 PM ET | First published: Oct 12, 2025, 12:03 AM ET

Written by Jason Bevilacqua, Head of Content and Communities

Get NFL player props today with projections for Sunday's Week 6 games.

NFL Prop Bets. — NFL prop bets for Week 6 are based on the latest odds and projections for Sunday's football games.

Our NFL player props for Sunday, October 12, 2025, are locked in, chosen through groundbreaking simulations and high-tech machine learning.

These NFL player props are designed to enhance your betting strategy and feature players such as Drew Sample, Xavier Worthy and Ja'Marr Chase.

Three of today's prop betting opportunities are listed below, with Dimers Pro subscribers receiving unlimited access to our full suite of prop picks and today's NFL player projections.

Today's full list of NFL prop bets is led by a player in the Cardinals vs. Colts game to go over his rushing attempts line, with our in-house predictive model identifying an edge of 37% at -110 odds.

Join Dimers Pro now to unlock this and more data-driven props and best bets.

List of NFL prop picks for Week 6

While the NFL prop picks on this page for Sunday are sorted by win probability, betting on likelihood alone means leaving money on the table.

Smart bettors chase edge—not just probability—and the highest-edge picks are reserved for Dimers Pro users to give them the best chance at winning.

Drew Sample over 0.5 receptions (-175)

Probability: 67.7%
Projection: 1.1
Edge: 4.1%
Game: Bengals vs. Packers (4:25PM ET)

Our model has found a standout NFL prop for the Bengals vs. Packers matchup in Week 6, focusing on Cincinnati's Drew Sample. With a 67.7% chance of hitting, we suggest betting on Drew Sample over 0.5 receptions at -175 odds, offering an edge of 4.1%.

Xavier Worthy under 7.5 rushing yards (-110)

Probability: 67.7%
Projection: 6.7
Edge: 15.3%
Game: Lions vs. Chiefs (8:20PM ET)

Our model has identified another high-probability prop for NFL Week 6, with Kansas City's Xavier Worthy in our sights in the Lions-Chiefs game. We recommend betting on Xavier Worthy under 7.5 rushing yards with an edge of 15.3% at -110 odds.

Ja'Marr Chase under 6.5 receptions (-126)

Probability: 65.0%
Projection: 5.7
Edge: 9.3%
Game: Bengals vs. Packers (4:25PM ET)

According to our analysis, another strong prop for this week's NFL focuses on Cincinnati's Ja'Marr Chase in the Bengals vs. Packers matchup. Our recommended bet is Ja'Marr Chase under 6.5 receptions at -126 odds, with a 65.0% chance of hitting and a 9.3% edge.

NFL player prop picks: Week 6, 2025

A quick summary of today’s top three props by probability according to our model as of 3:56PM ET:

Matchup	Prop	Odds	Probability	Edge
Bengals vs. Packers	Drew Sample Over 0.5 Receptions	-175 @ BetMGM	67.7%	4.1%
Lions vs. Chiefs	Xavier Worthy Under 7.5 Rushing Yards	-110 @ BetMGM	67.7%	15.3%
Bengals vs. Packers	Ja'Marr Chase Under 6.5 Receptions	-126 @ DraftKings	65.0%	9.3%

Get unlimited access to our full suite of prop picks by signing up for Dimers Pro.

Sunday's NFL props include a standout play with an edge of 37% on the best available odds—the kind of high-value bet you won't find by chasing probability alone.

Dimers Pro users have access to 172 NFL player props at the time of writing, all backed by real betting value.

NFL betting promos for Week 6

Make the most of today's player props—including Drew Sample over 0.5 receptions—with the two offers listed below.

DraftKings Sportsbook

Bet365 Sportsbook

Join Bet365 Sportsbookwith the bonus code "DIMERS" to unlock $200 in bonus bets.

More about NFL

The prop bets on this page are part of our NFL player props and NFL best bets series.

Stay updated with the latest NFL betting news, data-driven NFL predictions, NFL betting trends and Super Bowl odds.

Conclusion

For October 12, 2025, our NFL prop bets are locked and loaded, featuring players like Drew Sample, Xavier Worthy and Ja'Marr Chase. Powered by the latest data and cutting-edge simulations, these picks are here to give your betting strategy the edge it needs.

With the help of AI and automation, this article delivers today's NFL prop bets and insights quickly and accurately, while human oversight ensures high editorial quality. Our predictions are drawn from current data to help you make informed decisions.

For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

Note: Clicking links to our sportsbook partners may earn us a referral fee. Learn about how we review products and services.

Written by

Jason Bevilacqua

Head of Content and Communities

Jason Bevilacqua, an expert in MLB, NHL, NBA, MLS, and NFL, delivers game previews, best bets, and props. Since 2020, as Head of Social and Community at Dimers, he has contributed insightful articles utilizing data-driven models and simulations.

Advertiser disclosure