NFL picks straight up: Wild Card Weekend, 2026

At Dimers, our Wild Card Weekend NFL picks are grounded in data-driven insight, with straight-up picks for all six games informed by our latest NFL predictions.

Gain the edge in your NFL pick 'em contests with our data-driven NFL Wild Card picks straight up, powered by thousands of game simulations.

Wild Card Weekend begins with the Los Angeles Rams facing the Carolina Panthers on Saturday and ends with the Houston Texans taking on the Pittsburgh Steelers on Monday.

NFL picks this week straight up: Wild Card Weekend 2026

Listed below are our Wild Card Weekend NFL picks, highlighting how likely each team is to win their game this week.

Los Angeles Rams vs. Carolina Panthers

The Rams kick off this week's playoffs slate against the Panthers at Bank of America Stadium on Saturday. According to our model, the Rams have an 82% chance of winning, while the Panthers have an 18% chance.

For the weekend's opening game, our model highlights NFL player props with Kyren Williams (RB) as the most likely player from the Rams to score the first TD at 11.8%, while Rico Dowdle (RB) is the top candidate from the Panthers at 7.0%.

The Los Angeles Rams vs. Carolina Panthers game at Bank of America Stadium is scheduled for Saturday, January 10 at 4:30pm. All times stated in this article are in Eastern Standard Time (EST).

Green Bay Packers vs. Chicago Bears

For this week's game between the Packers and the Bears, Chicago is more likely to win. Our prediction model gives the Bears a 60% chance of winning. On the other hand, there is a 40% chance that the Packers will win.

The Green Bay Packers vs. Chicago Bears matchup at Soldier Field will take place on Saturday, January 10 at 8:00pm.

As the playoffs begin, track the top teams with our updated NFL futures, highlighting top Super Bowl contenders.

Buffalo Bills vs. Jacksonville Jaguars

We are picking the Bills to win their game against the Jaguars this week, with our famous NFL model projecting a 56% win probability for the road team. The Jaguars have a 44% chance of winning at EverBank Stadium.

For betting purposes, the Jaguars are listed as +1.5 underdogs, with the Bills' moneyline at -116.

The Buffalo Bills vs. Jacksonville Jaguars game at EverBank Stadium is slated for Sunday, January 11 at 1:00pm.

San Francisco 49ers vs. Philadelphia Eagles

According to our predictive analytics model, the Eagles are the team to beat in this game, with their win probability at 66%. The 49ers, on the other hand, have a 34% chance of winning.

The San Francisco 49ers vs. Philadelphia Eagles game at Lincoln Financial Field is set for Sunday, January 11 at 4:30pm.

Los Angeles Chargers vs. New England Patriots

The Patriots have a 63% chance of winning on Sunday night, compared to the Chargers' 37% chance of victory. This makes the New England Patriots our pick to win at Gillette Stadium.

The Los Angeles Chargers vs. New England Patriots matchup at Gillette Stadium is scheduled for Sunday, January 11 at 8:00pm.

Houston Texans vs. Pittsburgh Steelers

The Texans are favored to win their game this week, with our predictive analytics model giving them a 64% chance, while the Steelers enter the weekend with a 36% chance of causing an upset at Acrisure Stadium.

When it comes to betting on this game, the Texans' moneyline odds are set at -180, with the home team Steelers listed as +3.5 underdogs.

The Houston Texans vs. Pittsburgh Steelers game at Acrisure Stadium will take place on Monday, January 12 at 8:00pm.

Full list of NFL Wild Card picks straight up

• Rams (82% win probability)
• Bears (60%)
• Bills (56%)
• Eagles (66%)
• Patriots (63%)
• Texans (64%)

For more insights into this week's NFL predictions, check out the latest from the Dimers Sports Betting Podcast:

NFL straight up picks and predictions for Wild Card Weekend

The NFL Wild Card predictions straight up in this article are accurate at the time of publication but may change.

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Please note that all NFL odds and probabilities mentioned on this page are subject to change.