NFL Best Bets: Week 17 Picks Include Cardinals vs. Rams Play [12/28/2024]

NFL betting is back for another pulse-pounding day on 12/28, and we're here to give you our top picks for Saturday's football action.

Today's NFL best bets come from a range of matchups, including the Cardinals vs. Rams game at 8:10PM ET, with this article updated throughout the day to highlight the most attractive upcoming games.

Led by a standout spread play with an edge of 7.0%, these picks are based on extensive simulations and machine learning.

For unlimited access to everything Dimers has to offer on Saturday, December 28, 2024—including our full set of NFL picks and best bets—check out Dimers Pro.

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List of NFL Best Bets Tonight [12/28, Updated: 8:01PM ET]

After crunching the numbers and conducting thousands of simulations, our leading predictive analytics model has figured out the best football bets for Saturday, December 28, 2024.

We sort these picks by start times, reserving the highest edges and probabilities exclusively for Dimers Pro subscribers.

Cardinals +6.5 (+100)

• Edge: 7.0%
• Probability: 57%
• Matchup: Cardinals vs. Rams (8:10PM ET, Saturday)

Our model has pinpointed the next NFL betting opportunity tonight, which comes in the Cardinals vs. Rams game. We recommend a spread bet on Cardinals +6.5 at +100 odds, offering an edge of 7.0%.

Cardinals ML (+275)

• Edge: 2.9%
• Probability: 29.6%
• Matchup: Cardinals vs. Rams (8:10PM ET, Saturday)

Our model has found another great NFL bet for Saturday's sports action, again in the game between the Cardinals and Rams. We suggest placing a wager on Cardinals ML at +275 odds, with our analysis showing a compelling 2.9% edge.

MORE: NFL Props

NFL Best Bets: Saturday, 12/28/2024

As of 8:01PM ET, here are the next two NFL bets recommended by our model:

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While the bets listed are all positive expected value (+EV) opportunities, subscribing to Dimers Pro grants you unlimited access to today's best bets across all sports, powered by our advanced model.

Join Dimers Pro now to access these picks, along with a comprehensive range of props, trends and parlays for December 28, 2024.

List of Upcoming NFL Games to Bet On [12/28/2024]

• Cardinals vs. Rams (8:10PM ET, Saturday)
• Titans vs. Jaguars (1:00PM ET, Sunday)
• Panthers vs. Buccaneers (1:00PM ET, Sunday)
• Raiders vs. Saints (1:00PM ET, Sunday)
• Jets vs. Bills (1:00PM ET, Sunday)
• Cowboys vs. Eagles (1:00PM ET, Sunday)
• Colts vs. Giants (1:00PM ET, Sunday)
• Dolphins vs. Browns (4:05PM ET, Sunday)
• Packers vs. Vikings (4:25PM ET, Sunday)

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More About NFL

This article is part of our NFL player props and NFL best bets series.

For more NFL betting content, we have NFL trends for every game, as well as daily NFL betting news and the latest Super Bowl odds and predictions.

Conclusion

This article, enhanced by AI and automation, aims to deliver accurate NFL insights quickly, with human oversight ensuring high editorial quality. Our predictions are grounded in current data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

All odds and probabilities in this article are correct and accurate at the time of publication.