NFL best bets today: Christmas Day picks include Cowboys vs. Commanders play [12/25/2025]

Today’s NFL picks for Christmas Day are here, with Cowboys vs. Commanders among the top plays identified by our model across Thursday’s NFL schedule.

Dimers’ predictive analytics engine runs 24/7, scanning the latest football odds to find legitimate betting edges. The result? Data-backed plays that help Dimers Pro members make smarter decisions.

List of NFL best bets today [12/25, updated 12:35PM ET]

Below, you’ll find today’s best football bets, ranked by edge for Thursday, December 25, 2025.

Commanders ML (+380)

• Edge: 6.7%
• Probability: 27.6%
• Matchup: Cowboys vs. Commanders (1:00PM ET, Thursday)

Our model has identified value on Commanders to defeat Cowboys at +380 odds. A 27.6% probability produces an edge of 6.7%, making this the strongest play for today's NFL slate.

Commanders +8.5 (+100)

• Edge: 6.5%
• Probability: 56.5%
• Matchup: Cowboys vs. Commanders (1:00PM ET, Thursday)

Commanders +8.5 carries a 6.5% edge and a probability of 56.5% at +100 odds, according to our model.

NFL best bets summary: Thursday, 12/25/2025

As of 12:35PM ET, here are our top NFL bets by edge recommended by our model:

List of upcoming NFL games to bet on [12/25/2025]

• Cowboys vs. Commanders (1:00PM ET, Thursday)
• Lions vs. Vikings (4:30PM ET, Thursday)
• Broncos vs. Chiefs (8:15PM ET, Thursday)

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Conclusion

Our NFL best bets are locked and loaded for December 25, 2025, featuring plays such as Commanders ML and Commanders +8.5. Powered by advanced simulations, these picks are here to boost your betting game.

This article, enhanced by AI and automation, aims to deliver accurate NFL insights quickly, with human oversight ensuring high editorial quality. Our predictions are based on current data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

All odds and probabilities in this article are correct and accurate at the time of publication.

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